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  7. Anti-BCMA antibody(DM16), Rabbit mAb

Anti-BCMA antibody(DM16), Rabbit mAb

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Figure 1. Detection of BCMA/ TNFRSF 17 in K562-BCMA (K562 cells transduced with gene for full length BCMA) Human Cell Line or NCI-H929 Human Cell Line with Rabbit Anti-Human BCMA/TNFRSF 17 Antigen Affinity-purified monoclonal antibody (clone: DM16) by FACS.

Anti-BCMA antibody(DM16), Rabbit mAb
Anti-BCMA antibody(DM16), Rabbit mAb
Anti-BCMA antibody(DM16), Rabbit mAb
Anti-BCMA antibody(DM16), Rabbit mAb

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Figure 1. Detection of BCMA/ TNFRSF 17 in K562-BCMA (K562 cells transduced with gene for full length BCMA) Human Cell Line or NCI-H929 Human Cell Line with Rabbit Anti-Human BCMA/TNFRSF 17 Antigen Affinity-purified monoclonal antibody (clone: DM16) by FACS.
Figure 2. Binding of different clone Rabbit Anti-Human BCMA/TNFRSF 17 Antigen Affinity-purified monoclonal antibody to NCI-H929 and K562-BCMA cells was determined by FACS.
Figure 3. Phylogenetic analysis of different clone Rabbit Anti-Human BCMA/TNFRSF 17 Antigen Affinity-purified monoclonal antibody A) heavy chain and B) Light chain.
Figure 4. ELISA plate was coated with recombinant BCMA-hFc fusion protein , followed by pre-blocking with huC11D5.3 antibody (Grey bar) or rabbit control IgG (Black bar), and then different rabbit  antibodies were added to check the competitive inhibition of huC11D5.3. DM3 clone exhibits the strongest inhibition (Red bar). This data indicated that DM3 bind to the same epitope as bb2121.

Product code: 12-9016

Clone name : DM16
Clonality : Monoclonal
Application : ELISA
Reactivity : Human

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100 µg
$599.00 

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  • Antigen Details
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Amount : 100 µg
Isotype : Rabbit IgG
Purification : Purified from cell culture supernatant by affinity chromatography
Content : Preservative: 0.1% Procline 300
Constituents: 50% Glycerol; PBS, pH 7.4; 0.1% BSA
Storage condition : Store at -20°C for 12 months (Avoid repeated freezing and thawing)
Alternative Name : TNFRSF17, CD269, BCM, BCMA
Immunogen Information : Recombinant human BCMA (Met1-Ala54) produced by using human HEK293 cells

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.

Recommended Dilutions FACS  1/100; IP 1/30

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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Anti-BCMA antibody(DM16), Rabbit mAb

Product code: 12-9016
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