Cancer is a group of disorders characterized by changes in the status and expression of several genes that provide somatic or germinal cells an advantage in survival and unrestricted capacity for cell division. Biochemical signs indicating the existence of cancer are known as cancer markers. Tumor indicators might be proteins, conjugated proteins, peptides, or carbohydrates depending on their chemical makeup. The majority of gene sequencing for medical diagnosis falls under the biomarker category. In clinical practice, it refers to a chemical that may be found in plasma and bodily fluids. Oncologists utilize a variety of cancer markers to assist identify the presence of cancer, each of which is suggestive of a unique disease phase. The body either develops these indicators in reaction to malignant cell invasion or as a result of cancer cells (tumor-associated). Cancer markers are not the primary modalities for cancer diagnosis rather they can be used as laboratory tests to support the diagnosis.