Anti-CD10 (Membrane Metalloendopeptidase) Monoclonal Antibody(Clone: 56C6)
Fig. 1: Formalin-fixed, paraffin-embedded human Kidney stained with CD10 Mouse Monoclonal Antibody (56C6).
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Shipping Info:
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| Amount : | 0.5 ml |
| Isotype : | Mouse IgG1, kappa |
| Content : | Tissue culture supernatant with 0.05% Azide. Contact us if you require it in a different format. |
| Storage condition : | Store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. |
| Gene : | MME |
| Gene ID : | 4311 |
| Uniprot ID : | P08473 |
| Alternative Name : | Atriopeptidase; Common acute lymphocytic leukemia antigen (CALLA); Enkephalinase (EPN); gp100; Membrane metalloendopeptidase (MME); Neprilysin; Neutral endopeptidase (NEP); Skin fibroblast elastase (SFE) |
| Immunogen Information : | Recombinant human CD10 protein fragment |
Recognizes a 100kDa glycoprotein, identified as CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.
Immunohistochemistry (Formalin-fixed) (1:50-1:100 for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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