Anti-Hu CD156c PE Mab(11G2)
|Amount :||100 Tests|
|Isotype :||Mouse IgG1 kappa|
|Purification :||Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.|
|Content :||Formulation: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide|
|Storage condition :||Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.|
Specificity: The mouse monoclonal antibody 11G2 recognizes an extracellular/luminal epitope of CD156c, a type I transmembrane glycoprotein, serving as a zinc-dependent metalloprotease.
CD156c is a type I transmembrane glycoprotein with a zinc-dependent metalloprotease activity. It serves as an endopeptidase of broad specificity, which is expressed mainly in thymus, liver, and muscles. Its expression can be induced in inflamed central nervous system, and in arthritic tissues. CD156c is involved in multiple sclerosis-associated myelin degradation. It also solubilizes various membrane proteins, including CD23, CD44, CD126, CD171, ephrin-A2, and other.
Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. Extracellular and intracellular staining.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.