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  7. PAR4 Stable Cell Line-CHO-K1-Human(Currently Unavailable)

PAR4 Stable Cell Line-CHO-K1-Human(Currently Unavailable)

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Figure 1: Functional analysis of PAR4 receptor.

PAR4 Stable Cell Line-CHO-K1-Human(Currently Unavailable)

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Product code: 14-6078ACL

Application : Functional Assay
Reactivity : Human

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Amount : 2 vials
Content : Each Vial contains cells in 45% Ham's F12, 45% FBS, and 10% DMSO
Storage condition : Immediately upon receipt, store in liquid nitrogen.
Alternative Name : Human Recombinant PAR4 Proteinase-activated Receptor Stable Cell Line
Protease-activated receptor (PAR)-4 is a member of a unique family of GPCRs. The protease-activated receptors (PARs) that are activated by proteolytic cleavage of the N-terminal domain of the receptor reveal a tethered ligand. The PAR family consists of 4 receptors; PAR1 and PAR3 are activated by thrombin, and PAR2 and PAR4 are activated by several serine proteases (Macfarlane et al., 2001). PAR4 is a recently identified low-affinity thrombin receptor that plays a pathophysiological role in many types of tissues including the lung. Mice lacking PAR4 are protected from mesenteric arteriole thrombosis, indicating that PAR4 is a potential target for treatment of thrombosis in humans.

Application: Screen for antibodies through Flow Cytometry, Immunocytochemistry or Western blotting and analyzing receptors.
Culture Medium: Ham's F12, 10% FBS, 400 µg/ml G418

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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PAR4 Stable Cell Line-CHO-K1-Human(Currently Unavailable)

Product code: 14-6078ACL
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