Alexa Fluor 488 Conjugated Anti-Human CD303 Mab (Clone:15E3)

Figure 1: Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD303 (15E3) Alexa Fluor 488 antibody (4 μl reagent / 100 μl of peripheral whole blood).

Alexa Fluor 488 Conjugated Anti-Human CD303 Mab (Clone:15E3)

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Figure 1: Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD303 (15E3) Alexa Fluor 488 antibody (4 μl reagent / 100 μl of peripheral whole blood).

Figure 2: Flow cytometry multicolor surface staining pattern of human mononuclear cells using anti-human CD303 (15E3) Alexa Fluor 488 antibody (4 μl reagent / 100 μl of peripheral whole blood) and anti-human CD123 (6H6) APC antibody (10 μl reagent / 100 μl of peripheral whole blood).

Figure 3: Separation of human CD303 positive CD123 positive plasmacytoid DC (red-filled) from neutrophil granulocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD303 (15E3) Alexa Fluor 488 antibody (4 μl reagent / 100 μl of peripheral whole blood).

Product code: 30-2877AF488

Clone name :	15E3
Clonality :	Monoclonal
Application :	IHC-Fr, ICC, FACS
Reactivity :	Human

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For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Amount :	100 tests
Isotype :	Mouse IgG1 kappa
Purification :	Purified antibody is conjugated with Alexa Fluor 488 NHS ester under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Content :	Formulation: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage condition :	Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.


Gene :	CD303
Gene ID :	170482
Uniprot ID :	Q8WTT0
Alternative Name :	BDCA2; CLEC4C; DLEC; HECL; CLECSF7;CLECSF11; PRO34150
Immunogen Information :	CD303 ectodomain fused with human IgG Fc domain

CD303 is an approximately 38 kDa type II transmembrane glycoprotein with an extracellular C-type lectin domain. It is a specific marker of plasmacytoid dendritic cells, and plays roles in capturing of pathogen-related oligosaccharide-containing antigens by them, and in their presentation to T cells. CD303 also mediates a potent inhibition of interferon alpha/beta production in plasmacytoid dendritic cells, thus it represents a potential target for lupus erythematosus therapy.

Specificity: The mouse monoclonal antibody 15E3 recognizes an extracellular epitope of human CD303, a transmembrane glycoprotein expressed on plasmacytoid dendritic cells.

Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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