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  7. Anti-ACE2 antibody(DM47), Rabbit mAb

Anti-ACE2 antibody(DM47), Rabbit mAb

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Figure 1. Expi 293 cell line transfected with irrelevant protein (left) and human ACE2 (right) were surface stained with Rabbit anti-ACE2 monoclonal antibody 1µg/ml (clone: DM47) followed by Alexa 488-conjugated anti-rabbit IgG secondary antibody.

Anti-ACE2 antibody(DM47), Rabbit mAb
Anti-ACE2 antibody(DM47), Rabbit mAb
Anti-ACE2 antibody(DM47), Rabbit mAb

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Figure 1. Expi 293 cell line transfected with irrelevant protein (left) and human ACE2 (right) were surface stained with Rabbit anti-ACE2 monoclonal antibody 1µg/ml (clone: DM47) followed by Alexa 488-conjugated anti-rabbit IgG secondary antibody.
Figure 2. FACS data of serially titrated Rabbit anti-ACE2 monoclonal antibody (clone: DM47) on Expi 293 cell line transfected with human ACE2. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.
Figure 3. Affinity ranking of different Rabbit anti-ACE2 mAb clones by titration of different concentration onto Expi 293 cell line transfected with human ACE2. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.

Product code: 12-9037

Clone name : DM47
Clonality : Monoclonal
Application : ELISA, FACS
Reactivity : Human

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100 µg
$599.00 

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  • Product Info
  • Antigen Details
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Amount : 100 µg
Isotype : Rabbit IgG
Purification : Purified from cell culture supernatant by affinity chromatography
Content : Preservative: 0.1% Procline 300
Constituents: 50% Glycerol; PBS,pH 7.4; 0.1% BSA
Storage condition : Store at -20°C for 12 months (Avoid repeated freezing and thawing)
Alternative Name : ACE-2, ACEH, ACE2
Immunogen Information : Recombinant human ACE2 (Gln18-Ser740) produced by using human HEK293 cells

The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.

Recommended Dilutions ELISA 1/5000-10000;FACS  1/100

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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Anti-ACE2 antibody(DM47), Rabbit mAb

Product code: 12-9037
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