Anti-AGR2 antibody(2F4), Rabbit mAb
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| Amount : | 10 μg |
| Isotype : | Rabbit mAb |
| Purification : | Purified from cell culture supernatant by affinity chromatography |
| Content : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % � 8% trehalose is added as protectants before lyophilization. |
| Storage condition : | Store at -20�C to -80�C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80�C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Gene : | AGR2 |
| Uniprot ID : | O95994 |
| Alternative Name : | AG-2;hAG-2;HPC8 |
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression. [provided by RefSeq, Mar 2017]
ELISA 1/5000-10000
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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