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  7. Anti-BSEP Monoclonal Antibody (Clone:IHC518)

Anti-BSEP Monoclonal Antibody (Clone:IHC518)

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Figure 1: Immunohistochemical analysis of BSEP (Clone: IHC518) on Liver

Anti-BSEP Monoclonal Antibody (Clone:IHC518)

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Product code: 44-1006

Clone name : IHC518
Clonality : Monoclonal
Application : IHC
Reactivity : Human

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  •   0.1 ml

  •  0.5 ml

  • $394.00 

  • $1,050.00 

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Format : Purified
Amount : 0.5 ml
Isotype : Mouse IgG1
Purification : Protein A/G Chromatography
Content : Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
Storage condition : Store at 2°C - 8°C. Do not freeze.
Gene : ABCB11
Gene ID : 8647
Uniprot ID : O95342
Alternative Name : ABCB11, BSEP
Immunogen Information : Recombinant Human BSEP

Bile Salt Export Pump (BSEP) is a member of the ATP-binding cassette (ABC) transporters, which mediates the transport of bile acid, taurocholate and other cholate conjugates across the hepatocyte canalicular membrane into the canaliculus. BSEP is associated with progressive familial intrahepatic cholestasis type 2 (PFIC2) and benign recurrent intrahepatic cholestasis type 2 (BRIC2). PFIC2 caused by mutations in the BSEP gene increases the risk of hepatocellular carcinoma in early life

Recommended dilutions: Immunohistochemical analysis: 1:100 - 1:200. However, this need to be optimized based on the research applications.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Membrane
Tissue Specificity: Expressed predominantly, if not exclusively in the liver, where it was further localized to the canalicular microvilli and to subcanalicular vesicles of the hepatocytes by in situ.
BioGrid: 114199. 5 interactions.
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Anti-BSEP Monoclonal Antibody (Clone:IHC518)

Product code: 44-1006
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