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    7. Anti-BSEP Monoclonal Antibody (Clone:IHC518)

    Anti-BSEP Monoclonal Antibody (Clone:IHC518)

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    Figure 1: Immunohistochemical analysis of BSEP (Clone: IHC518) on Liver

    Anti-BSEP Monoclonal Antibody (Clone:IHC518)

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    Product code: 44-1006

    Clone name : IHC518
    Clonality : Monoclonal
    Application : IHC
    Reactivity : Human

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    •   0.1 ml

    •  0.5 ml

    • $394.00 

    • $1,050.00  $840.00 

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    • Product Info
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    • Review   (0)
    Format : Purified
    Amount : 0.5 ml
    Isotype : Mouse IgG1
    Purification : Protein A/G Chromatography
    Content : Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
    Storage condition : Store at 2°C - 8°C. Do not freeze.
    Gene : ABCB11
    Gene ID : 8647
    Uniprot ID : O95342
    Alternative Name : ABCB11, BSEP
    Immunogen Information : Recombinant Human BSEP

    Bile Salt Export Pump (BSEP) is a member of the ATP-binding cassette (ABC) transporters, which mediates the transport of bile acid, taurocholate and other cholate conjugates across the hepatocyte canalicular membrane into the canaliculus. BSEP is associated with progressive familial intrahepatic cholestasis type 2 (PFIC2) and benign recurrent intrahepatic cholestasis type 2 (BRIC2). PFIC2 caused by mutations in the BSEP gene increases the risk of hepatocellular carcinoma in early life

    Recommended dilutions: Immunohistochemical analysis: 1:100 - 1:200. However, this need to be optimized based on the research applications.

    For Research Use Only. Not for use in diagnostic/therapeutics procedures.

    Subcellular location: Membrane
    Tissue Specificity: Expressed predominantly, if not exclusively in the liver, where it was further localized to the canalicular microvilli and to subcanalicular vesicles of the hepatocytes by in situ.
    BioGrid: 114199. 5 interactions.
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    Anti-BSEP Monoclonal Antibody (Clone:IHC518)

    Product code: 44-1006
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