Anti-CD147 / EMMPRIN / Neurothelin Monoclonal Antibody(Clone: CB43)
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| Amount : | 100 µg |
| Isotype : | Mouse IgM, kappa |
| Content : | 200 µg/ml of Ab Purified from Bioreactor Concentrate. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Storage condition : | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. |
| Gene : | BSG |
| Gene ID : | 682 |
| Uniprot ID : | P35613 |
| Alternative Name : | 5A11 Antigen; 5F7; Basigin; Blood brain barrier HT7 antigen BSG; Emmprin; Extracellular Matrix Metalloproteinase Inducer; Leukocyte Activation Antigen M6; Neurothelin; OK Blood Group Antigen; TCSF; Tumor Cell-derived Collagenase Stimulatory Factor |
| Immunogen Information : | Native human leucocytes |
CD147 is a transmembrane glycoprotein of the immunoglobulin superfamily. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is involved in the regulation of matrix remodeling at the epidermal-dermal interface. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes, which are typically increased during tissue degradation and wound healing, are important factors in cancer invasion and metastasis.
Flow Cytometry (0.5-1µg/million cells); Immunofluorescence (0.5-1µg/ml); Optimal dilution for a specific application should be determined.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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