Anti-CD357 / GITR Monoclonal Antibody(Clone: GITR/1585)
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| Amount : | 100 µg |
| Isotype : | Mouse IgG3, kappa |
| Content : | 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Storage condition : | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. |
| Gene : | TNFRSF18 |
| Gene ID : | 8784 |
| Uniprot ID : | Q9Y5U5 |
| Alternative Name : | Activation inducible TNFR family receptor; AITR; GITRD; Glucocorticoid induced TNFR related protein; Glucocorticoid-induced TNFR-related protein; TNF receptor superfamily activation inducible protein; TNFRSF18 |
| Immunogen Information : | Human full-length TNFRSF18 protein |
The tumor necrosis factor receptor (TNFR) superfamily represents a growing family of type I transmembrane glycoproteins that are involved in various cellular functions, including proliferation, differentiation and programmed cell death. These proteins share homology for cysteine-rich repeats in the extracellular ligand binding domain and an intracellular death domain. Members of the TNFR superfamily transmit signals throµgh protein-protein interactions, and these signals can lead to the activation of either the caspase and Jun kinase pathways, which promote cell death, or the NFB signaling pathway.
ELISA (For coating, order Ab without BSA & Azide);Optimal dilution for a specific application should be determined.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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