Anti-CD38 antibody(DM30), Rabbit mAb(Discontinued)

Figure 1. Expi 293 cell line transfected with irrelevant protein (left) and human CD38 (right) were surface stained with Rabbit anti-CD38 monoclonal antibody 1µg/ml (clone: DM30) followed by Alexa 488-conjugated anti-rabbit IgG secondary antibody.

Anti-CD38 antibody(DM30), Rabbit mAb(Discontinued)

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Figure 1. Expi 293 cell line transfected with irrelevant protein (left) and human CD38 (right) were surface stained with Rabbit anti-CD38 monoclonal antibody 1µg/ml (clone: DM30) followed by Alexa 488-conjugated anti-rabbit IgG secondary antibody.

Figure 2. FACS data of serially titrated Rabbit anti-CD38 monoclonal antibody (clone: DM30) on Raji cells. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.

Figure 3. Affinity ranking of different Rabbit anti-CD38 mAb clones by titration of different concentration onto Raji cells. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.

Product code: 12-9021

Clone name :	DM30
Clonality :	Monoclonal
Application :	ELISA, FACS
Reactivity :	Human

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Download TDS MSDS

Amount :	100 µg
Isotype :	Rabbit IgG
Purification :	Purified from cell culture supernatant by affinity chromatography
Content :	Preservative: 0.1% Procline 300 Constituents: 50% Glycerol; PBS,pH 7.4; 0.1% BSA Not Sterile
Storage condition :	Store at -20°C for 12 months (Avoid repeated freezing and thawing)


Alternative Name :	T10, cADPr hydrolase 1
Immunogen Information :	Recombinant humanÂ CD38Â (Val43-IIe300) produced by using human HEK293 cells

CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.

Recommended Dilutions ELISA 1/5000-10000; FACS 1/100

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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