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  7. Anti-CD80 (B7-1) Monoclonal Antibody(Clone: C80/2776)

Anti-CD80 (B7-1) Monoclonal Antibody(Clone: C80/2776)

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Fig. 1: SDS-PAGE Analysis Purified CD80 Mouse Monoclonal Antibody (C80/2776). Confirmation of Purity and Integrity of Antibody

Anti-CD80 (B7-1) Monoclonal Antibody(Clone: C80/2776)
Anti-CD80 (B7-1) Monoclonal Antibody(Clone: C80/2776)

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Fig. 1: SDS-PAGE Analysis Purified CD80 Mouse Monoclonal Antibody (C80/2776). Confirmation of Purity and Integrity of Antibody
Fig. 2: Analysis of Protein Array containing more than 19,000 full-length human proteins using CD80 Mouse Monoclonal Antibody (C80/2776) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (Monoclonal Antibody) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target, if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.

Product code: 36-3573

Clone name : C80/2776
Clonality : Monoclonal
Application : ELISA
Reactivity : Human

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  •   20 µg

  •  100 µg

  • $199.00 

  • $459.00 

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  • Product Info
  • Antigen Details
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Amount : 100 µg
Isotype : Mouse IgG2b, kappa
Content : 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition : Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Gene : CD80
Gene ID : 941
Uniprot ID : P33681
Alternative Name : Activation B7-1 antigen; B lymphocyte activation antigen B7; B7; B7-1; BB1; CD28 antigen ligand 1; CD28LG; CD28LG1; CD80; Costimulatory factor CD80; CTLA-4 counter-receptor B7.1; LAB7; T-lymphocyte activation antigen CD80
Immunogen Information : Recombinant fragment of human CD80 protein (around aa 35-142) (exact sequence is proprietary)
T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.

ELISA (For coating, order Ab without BSA); Optimal dilution for a specific application should be determined.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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Anti-CD80 (B7-1) Monoclonal Antibody(Clone: C80/2776)

Product code: 36-3573
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