Anti-CD81 Monoclonal Antibody (Clone:M38)-APC Conjugated
Figure 1: Surface staining of CD81 in human peripheral blood with anti-CD81 (M38) APC.
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| Amount : | 100 tests |
| Isotype : | Mouse IgG1 |
| Storage condition : | Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. |
CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells - e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.
| Subcellular location: | Basolateral cell membrane |
| Post transnational modification: | Not glycosylated. |
| Tissue Specificity: | Hematolymphoid, neuroectodermal and mesenchymal tumor cell lines. |
| BioGrid: | 107413. 201 interactions. |
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