Anti-CD82 Monoclonal Antibody (Clone:C33)
Figure 1: Immunohistochemistry staining of human tonsil (paraffin-embedded sections) with anti-CD82 (C33).
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| Format : | Purified |
| Amount : | 0.1 mg |
| Isotype : | Mouse IgG2a |
| Purification : | Purified by protein-A affinity chromatography |
| Storage condition : | Store at 2-8°C. Do not freeze. |
CD82 (KAI1), a member of the tetraspanin family, forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules. These complexes influence adhesion, morphology, activation, proliferation and differentiation of B, T and other cells. CD82 regulates cytoskeleton rearrangement and may participate in the turnover of the tetraspanin complex members. Besides in the plasma membrane, CD82 is localized also in endosome/lysosome compartments. Tumour-suppressive roles of CD82 have been demonstrated.
| Subcellular location: | Membrane |
| Tissue Specificity: | Lymphoid specific. |
| BioGrid: | 109935. 24 interactions. |
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