Anti-DKK1(sirexatamab biosimilar) mAb
Figure 1. Flow cytometry analysis under cell membrane permeable condition with 1 μg/mL Anti-DKK1 (sirexatamab biosimilar) mAb on Expi293 cells transfected with Human DKK1 protein (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
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Shipping Info:
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| Amount : | 100 µg |
| Isotype : | IgG4 |
| Purification : | Purified from cell culture supernatant by affinity chromatography |
| Content : | Not Sterile |
| Storage condition : | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized proteins are shipped at ambient temperature. |
| Alternative Name : | DKK-1, SK |
Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals.
FACS 1:100
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
Wang L, Peterson SM, Yang M, Lujan Hernandez AG, Yuan TZ, Han Z, Prabhu V, Chan KY, Hu CF, Villalta M, Htoy T, VanDyke P, Holliday C, Franco H, Wadhwa H, Giang H, Stafford R, Axelrod F, Sato A.
A multi-faceted discovery strategy identifies functional antibodies binding to cysteine-rich domain 1 of hDKK1 for cancer immunotherapy via Wnt non-canonical pathway.
Oncogene. 2025 May 20. doi: 10.1038/s41388-025-03445-6. Online ahead of print.
PMID: 40394415
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