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  7. Anti-Granzyme B FITC (Clone : CLB-GB11)

Anti-Granzyme B FITC (Clone : CLB-GB11)

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Figure 1 : Flow cytometry intracellular staining pattern of human peripheral whole blood stained using anti-human Granzyme B (CLB-GB11) FITC antibody (4 µl reagent / 100 µl of peripheral whole blood).

Anti-Granzyme B FITC (Clone : CLB-GB11)
Anti-Granzyme B FITC (Clone : CLB-GB11)
Anti-Granzyme B FITC (Clone : CLB-GB11)

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Figure 1 : Flow cytometry intracellular staining pattern of human peripheral whole blood stained using anti-human Granzyme B (CLB-GB11) FITC antibody (4 µl reagent / 100 µl of peripheral whole blood).
Figure 2 : Flow cytometry multicolor intracellular staining of human lymphocytes stained using anti-human Granzyme B (CLB-GB11) FITC antibody (4 µl reagent / 100 µl of peripheral whole blood) and anti-human CD3 (UCHT1) APC antibody (10 µl reagent / 100 µl of peripheral whole blood).
Figure 3 :Separation of human CD3 negative Granzyme B positive lymphocytes (red-filled) from CD3 negative Granzyme B negative lymphocytes (black-dashed) in flow cytometry analysis (intracellular staining) of human peripheral whole blood stained using anti-human Granzyme B (CLB-GB11) FITC antibody (4 µl reagent / 100 µl of peripheral whole blood).

Product code: 30-2530

Clone name : CLB-GB11
Clonality : Monoclonal
Application : FACS
Reactivity : Human
Conjugate : FITC

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100 tests
$565.00 

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  • Product Info
  • Antigen Details
  • Description
  • Application Note
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Amount : 100 tests
Isotype : Mouse IgG1
Purification : The purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Content : Formulation : Stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Gene : GZMB
Gene ID : 3002
Alternative Name : GZMB, HLP, CTLA1, SECT,granzyme B
Immunogen Information : Human NK cell line YT-INDY-derived granzyme B
Granzyme B is a serine protease that is expressed in cytoplasmic granules of cytotoxic T lymphocytes and NK cells. Vectorial secretion of perforin and granzymes is responsible for their granule-mediated cytotoxicity. Granzyme B plays a pivotal role in the induction of apoptosis in the target cells by activation of caspases. Moreover, granzyme B was reported to cleave directly alpha-tubulin, leading to perturbation of microtubule networks during the induced cell death.
Specificity : The mouse monoclonal antibody CLB-GB11 recognizes granzyme B, a 31 kDa serine protease expressed intracellularly in activated Tc cells and NK cells.

Flow cytometry: The reagent is designed for analysis of human blood cells using 4 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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Anti-Granzyme B FITC (Clone : CLB-GB11)

Product code: 30-2530
*specify in mg or ml

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