Anti-HLA-E Antibody (Clone : 3D12)

Name: Anti-HLA-E Antibody (Clone : 3D12)
Brand: Abeomics
SKU: 30-2520
Price: 399.0000 USD
Availability: InStock
Rating: 4.5 (10 reviews)

Figure 1 : Flow cytometry surface staining pattern of human peripheral blood stained using anti-human HLA-E (3D12) purified antibody (concentration in sample 4 µg/ml) GAM APC.

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Figure 1 : Flow cytometry surface staining pattern of human peripheral blood stained using anti-human HLA-E (3D12) purified antibody (concentration in sample 4 µg/ml) GAM APC.

Figure 2 : Separation of human lymphocytes (red-filled) from blood debris (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human HLA-E (3D12) purified antibody (concentration in sample 4 µg/ml) GAM APC.

Product code: 30-2520

Clone name :	3D12
Clonality :	Monoclonal
Application :	FACS , IP, ELISA
Reactivity :	Human

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Download TDS MSDS

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Shipping Info:

For estimated delivery dates, please contact us at support@abeomics.com

Download TDS MSDS

Format :	Purified
Amount :	0.1 mg
Isotype :	Mouse IgG1
Purification :	Purified from cell culture supernatant by protein-A affinity chromatography
Content :	1 mg/ml Formulation : Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage condition :	Store at 2-8°C. Do not freeze.


Gene :	HLA-E
Gene ID :	3133
Alternative Name :	HLA class I histocompatibility antigen, alpha chain E, MHC class I antigen E,major histocompatibility complex, class I, E

HLA-E (Human Leukocyte Antigen E) is a non-classical MHC I antigen, which is important for dialogue with NK cells and their regulation through interaction with CD94/NKG2 receptor. Like other MHC I molecules, transmembrane HLA-E molecule (45 kDa) associates with beta2 microglobulin. Unlike HLA-G, expression of HLA-E molecules is not so restricted, but it has been detected at least at mRNA level in virtually all cells and tissues examined. In peripheral blood, HLA-E protein is expressed at least in all mononuclear cells, but in different quantity (B cells and monocytes more than T cells and NK cells).
Specificity : The mouse monoclonal antibody 3D12 (also known as 3D12HLA-E) recognizes native extracellular part of HLA-E, an ubiquitously expressed non-classical MHC class I molecule, as well as free HLA-E.

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