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  7. Anti-HLA-F Antibody (Clone : 3D11)

Anti-HLA-F Antibody (Clone : 3D11)

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Anti-HLA-F Antibody (Clone : 3D11)

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Product code: 30-2518

Clone name : 3D11
Clonality : Monoclonal
Application : FACS , WB
Reactivity : Human

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0.1 mg
$399.00 

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  • Product Info
  • Antigen Details
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Format : Purified
Amount : 0.1 mg
Isotype : Mouse IgG1
Purification : Purified by protein-A affinity chromatography
Content : 1 mg/ml
Formulation : Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage condition : Store at 2-8°C. Do not freeze.
Gene : HLA-F
Gene ID : 3134
Alternative Name : CDA12,major histocompatibility complex, class I, F
Immunogen Information : Inclusion body-derived HLA-F heavy chain
HLA-F, an MHC class I molecule, is a type I transmembrane protein (heavy chain), which forms heterodimers with beta-2 microglobulin (light chain) and binds to KIR3DS1, KIR3DS4, KIR3DL2, ILT2, ILT4, and TAP. Unlike most other HLA proteins, HLA-F is mainly localized in the endoplasmic reticulum and Golgi apparatus, with only a small amount present on the cell surface in some cell types; surface expression can be induced by cell activation. It is thought to bind a restricted subset of peptides for immune presentation. Multiple transcript variants encoding different isoforms have been found for HLA-F gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain.
Specificity : The mouse monoclonal antibody 3D11 recognizes an extracellular epitope of HLA-F, a 42 kDa type I transbembrane protein expressed on B cells, NK cells, monocytes, and T cells, but mainly in the endoplasmic reticulum and Golgi apparatus, only a small amount on the cell surface, where, however, it can be expressed after cell activation.
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Anti-HLA-F Antibody (Clone : 3D11)

Product code: 30-2518
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