Abeomics Logo
  • (0) Items
    • Items | total: $0.00 (0)
    • Your shopping cart is empty!

Abeomics Logo

Antibodies & Engineered Cell Lines™

  • Account
    • Login
    • Address Book
    • My Order
    • My Wish List
    • Open a New Ticket
  • (0) Items
    • Your shopping cart is empty!

  • About us
  • Products
      • Antibodies
        • Biosimilars
        • TLR and Innate Immunity
        • Apoptosis
        • Immunology
        • DNA methylation and Repair
        • Cell Signalling
        • Infectious Diseases
        • NF-kB Pathway
        • Cancer Marker
        • Loading Controls
        • Stem Cells
        • Development and Differentiation
        • Isotype Controls
        • Secondary Antibodies
        • Tag Antibodies
        • Miscellaneous
      • Cell Lines
        • Reporter Cell Lines
        • Stable Cell Lines
      • Ligands and Inhibitors
        • Peptide Inhibitors
        • Proteases inhibitors
        • TLR Ligands
        • Caspase Inhibitors
      • Recombinant Proteins
        • Recombinant Proteins
      • Immune-Check Point
      • Kits and Reagents
        • Other Kits
        • Luciferase reporter assay kits
        • Inhibitor Screening Kit
        • ELISA Kits
        • Molecular Biology Kits
        • Apoptosis Detection kits
        • Flowcytometry staining kits
        • Cell dissociation solutions
        • Western Blot membranes (Quick blots/ Q Blots)
      • Tissue Microarray
      • recmAb™
        • Recombinant Biosimilar Antibodies
        • Recombinant Rabbit Antibodies
        • Recombinant Mouse Antibodies
  • Pathways
      • All-Pathways

        View all pathways

      • interactive-pathways

        View all interactive pathways

  • Custom Service
    • Drug Discovery Screening Services
    • Stable Cell Line Development
    • Protein Production
    • Custom Antibody Development
  • Quick order
    • + Add More..

  • Support
  • Contact us
  • Distributors
  1. Catalog
  2. /
  3. Antibodies
  4. /
  5. Cell Signalling
  6. /
  7. Anti-HSP90 alpha Monoclonal Antibody (Clone : Hyb-K41009) Alkaline Phosphatase(Discontinued)

Anti-HSP90 alpha Monoclonal Antibody (Clone : Hyb-K41009) Alkaline Phosphatase(Discontinued)

Share:

Figure1 : Mouse Anti-Hsp90 alpha Antibody [Hyb-K41009] used in Immunohistochemistry (IHC) on Human colon carcinoma

Anti-HSP90 alpha Monoclonal Antibody (Clone : Hyb-K41009) Alkaline Phosphatase(Discontinued)
Anti-HSP90 alpha Monoclonal Antibody (Clone : Hyb-K41009) Alkaline Phosphatase(Discontinued)
Anti-HSP90 alpha Monoclonal Antibody (Clone : Hyb-K41009) Alkaline Phosphatase(Discontinued)

Roll over image to zoom in

   
Figure1 : Mouse Anti-Hsp90 alpha Antibody [Hyb-K41009] used in Immunohistochemistry (IHC) on Human colon carcinoma
Figure 2 :  Mouse Anti-Hsp90 alpha Antibody [Hyb-K41009] used in Western Blot (WB) on Rat Lysates
Figure 3 :  Mouse Anti-Hsp90 alpha Antibody [Hyb-K41009] used in Immunohistochemistry (IHC) on Mouse inflamed colon

Product code: 42-1082

Clone name : Hyb-K41009
Clonality : Monoclonal
Application : ELISA, IHC, WB
Reactivity : Rat, Mouse, Human

Shipping Info:

For estimated delivery dates, please contact us at support@abeomics.com

Download TDS MSDS
Write a review for this product on BioCompare
Get $20 gift card from Amazon

Shipping Info:

For estimated delivery dates, please contact us at support@abeomics.com

Download TDS MSDS

  • Product Info
  • Antigen Details
  • Description
  • Application Note
  • More
  • Review   (0)
Amount : 100 µg
Isotype : Mouse IgG2a
Purification : Protein G Purified
Content : PBS pH7.2, 50% glycerol, 0.09% sodium azide
Storage condition : Store the antibody at 4°C
Gene : HSP90AA1
Gene ID : 3320
Uniprot ID : P07900
Alternative Name : HSP90AA1, HSP90A, HSPC1, HSPCA
Immunogen Information : Recombinant human HSP90alpha; Specificity mapped to amino acids 604-731

HSP90 is an abundantly and ubiquitously expressed heat shock protein. It is understood to exist in two principal forms alpha and beta, which share 85% sequence amino acid homology. The two isoforms of HSP90, are expressed in the cytosolic compartment. Despite the similarities, HSP90 alpha exists predominantly as a homodimer while HSP90 beta exists mainly as a monomer. From a functional perspective, HSP90 participates in the folding, assembly, maturation, and stabilization of specific proteins as an integral component of a chaperone complex. Furthermore, HSP90 is highly conserved between species; having 60% and 78% amino acid similarity between mammalian and the corresponding yeast and Drosophila proteins, respectively. HSP90 is a highly conserved and essential stress protein that is expressed in all eukaryotic cells. Despite it’s label of being a heat-shock protein, HSP90 is one of the most highly expressed proteins in unstressed cells (1–2% of cytosolic protein). It carries out a number of housekeeping functions – including controlling the activity, turnover, and trafficking of a variety of proteins. Most of the HSP90-regulated proteins that have been discovered to date are involved in cell signaling. The number of proteins now know to interact with HSP90 is about 100. Target proteins include the kinases v-Src, Wee1, and c-Raf, transcriptional regulators such as p53 and steroid receptors, and the polymerases of the hepatitis B virus and telomerase. When bound to ATP, HSP90 interacts with co-chaperones Cdc37, p23, and an assortment of immunophilin-like proteins, forming a complex that stabilizes and protects target proteins from proteasomal degradation. In most cases, HSP90-interacting proteins have been shown to co-precipitate with HSP90 when carrying out immunoadsorption studies, and to exist in cytosolic heterocomplexes with it. In a number of cases, variations in HSP90 expression or HSP90 mutation has been shown to degrade signaling function via the protein or to impair a specific function of the protein (such as steroid binding, kinase activity) in vivo. Ansamycin antibiotics, such as geldanamycin and radicicol, inhibit HSP90 function.

WB (1:1000), IHC (1:5000); optimal dilutions for assays should be determined by the user.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Nucleus, Cytoplasm, Melanosome, Cell membrane
Post transnational modification: S-nitrosylated; negatively regulates the ATPase activity and the activation of eNOS by HSP90AA1.
BioGrid: 109552. 856 interactions.
There are currently no product reviews
Write a review on this product!

Customers who purchased this product also purchased

Monoclonal Antibody to Kappa (Clone: ABM3A47)

Monoclonal Antibody to Kappa (...

details-Monoclonal Antibody to Kappa (Clone: ABM3A47)
Monoclonal Antibody to Rat C6 (clone: 3G11)

Monoclonal Antibody to Rat C6 ...

details-Monoclonal Antibody to Rat C6 (clone: 3G11)
Anti-Human CD143 Antibody (Clone : 5-369)

Anti-Human CD143 Antibody (Clo...

details-Anti-Human CD143 Antibody (Clone : 5-369)
Anti-Survivin Monoclonal Antibody (Clone:IHC668)

Anti-Survivin Monoclonal Antib...

details-Anti-Survivin Monoclonal Antibody (Clone:IHC668)
CD5L Recombinant Protein

CD5L Recombinant Protein

details-CD5L Recombinant Protein
Anti-CD40 Antibody (iscalimab biosimilar)(CFZ-533)

Anti-CD40 Antibody (iscalimab ...

details-Anti-CD40 Antibody (iscalimab biosimilar)(CFZ-533)
Anti-CS1 antibody(DM11), Rabbit mAb

Anti-CS1 antibody(DM11), Rabbi...

details-Anti-CS1 antibody(DM11), Rabbit mAb
Monoclonal Antibody to human ICAM-1

Monoclonal Antibody to human I...

details-Monoclonal Antibody to human ICAM-1
Monoclonal Antibody to CD10 (Clone: ABM4A52)

Monoclonal Antibody to CD10 (C...

details-Monoclonal Antibody to CD10 (Clone: ABM4A52)
TXNRD1 161-649 Recombinant Protein

TXNRD1 161-649 Recombinant Pro...

details-TXNRD1 161-649 Recombinant Protein
Monoclonal Antibody to human CD55

Monoclonal Antibody to human C...

details-Monoclonal Antibody to human CD55
AMBP Recombinant Protein

AMBP Recombinant Protein

details-AMBP Recombinant Protein
Recombinant Human X-Ray Repair Cross Complementing Protein 2

Recombinant Human X-Ray Repair...

details-Recombinant Human X-Ray Repair Cross Complementing Protein 2
REV1 Recombinant Protein

REV1 Recombinant Protein

details-REV1 Recombinant Protein

Most viewed Products

Recombinant Human Thioredoxin-Like 4A

Recombinant Human Thioredoxin-Like ...

details-Recombinant Human Thioredoxin-Like 4A
NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line

NF-kB Leeporter™ Luciferase Repor...

details-NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line
Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)

Monoclonal Antibody to Human IL-1be...

details-Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)
Polyclonal Antibody to Beta actin

Polyclonal Antibody to Beta actin

details-Polyclonal Antibody to Beta actin
Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)

Monoclonal Antibody to Caspase-3 (P...

details-Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)
Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)

Monoclonal antibody to Human PD-L1 ...

details-Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)
Monoclonal Antibody to GAPDH (Clone: ABM22C5)

Monoclonal Antibody to GAPDH (Clone...

details-Monoclonal Antibody to GAPDH (Clone: ABM22C5)
Monoclonal antibody to B7-H4 (Clone: ABM53A6)

Monoclonal antibody to B7-H4 (Clone...

details-Monoclonal antibody to B7-H4 (Clone: ABM53A6)
Recombinant Human Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His)

Recombinant Human Indoleamine 2,3-D...

details-Recombinant Human Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His)
Polyclonal Antibody to Beta Tubulin

Polyclonal Antibody to Beta Tubulin

details-Polyclonal Antibody to Beta Tubulin

Related Products

Anti-PLSCR1 Monoclonal Antibody (Clone:13A6 [TEC-23])

Anti-PLSCR1 Monoclonal Antibody (Clone:13A6 [TEC-23])

Phospho-Zap70 (Tyr319)/Syk (Tyr352) (Clone: A3) rabbit mAb

Phospho-Zap70 (Tyr319)/Syk (Tyr352) (Clone: A3) rabbit mAb

Anti-HSP70 Monoclonal Antibody (Clone : 5A5) - PerCP

Anti-HSP70 Monoclonal Antibody (Clone : 5A5) - PerCP

New Products

Recombinant TLR9 Protein with human Fc Tag

Recombinant TLR9 Protein with human Fc Tag

Anti-TLR2 Antibody (tomaralimab biosimilar)

Anti-TLR2 Antibody (tomaralimab biosimilar)

Anti-PD-1(Opdivo)(Nivolumab biosimilar) mAb

Anti-PD-1(Opdivo)(Nivolumab biosimilar) mAb

close

Please Login to write a Review !!


close

Anti-HSP90 alpha Monoclonal Antibody (Clone : Hyb-K41009) Alkaline Phosphatase(Discontinued)

Product code: 42-1082
*specify in mg or ml

Abeomics Logo

Antibodies & Engineered Cell Lines™

Tel : 858-263-4982

Fax : 858-247-7052

Email : support@abeomics.com

Connect with Us

  • Facebook
  • Twitter
  • Linkedin
  • YouTube

Products

  • Antibodies
  • Cell Lines
  • Ligands and Inhibitors
  • Recombinant Proteins
  • Immune-Check Point
  • Kits and Reagents
  • Tissue Microarray
  • recmAb™

Services

  • Drug Discovery Screening Services
  • Stable Cell Line Development
  • Protein Production
  • Custom Antibody Development

Quick order

+ Add More..

Newsletter

Posters and Flyers

© 2023 Abeomics. All rights reserved.
  • Blog
  • Sitemap
  • Terms
  • Privacy Policy
  • Legal
  • Email unsubscribe

Item added to cart successfully

No cart item available
Continue shopping View Cart