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  7. Anti-Human CD100 PE (Clone : 133-1C6)

Anti-Human CD100 PE (Clone : 133-1C6)

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Figure 1 : Flow cytometry analysis (surface staining) of human peripheral blood with anti-CD100 (133-1C6) PE.

Anti-Human CD100 PE (Clone : 133-1C6)

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Product code: 30-2669

Clone name : 133-1C6
Clonality : Monoclonal
Application : FACS
Reactivity : Human
Conjugate : PE

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100 tests
$443.00 

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  • Antigen Details
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Amount : 100 tests
Isotype : Mouse IgM
Purification : The purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Content : Formulation : Stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Gene : SEMA4D
Gene ID : 10507
Alternative Name : COLL4, SEMA4D, semaphorin 4D,semaphorin 4D
Immunogen Information : PHA stimulated human PBL
CD100, also known as Semaphorin 4D, is a homodimerizing type I transmembrane glycoprotein containing an extracellular semaphorin domain. It is expressed on most hematopoietic cells with the exception of immature bone marrow cells, erythrocytes and platelets. A 120 kDa soluble form is generated from the transmembrane form by proteolytic cascade following primary T and B cell activation. It seems CD100 acts through dampening CD72-mediated negative signaling. CD100 promotes angiogenesis, invasive growth, proliferation and anti-apoptosis of cancer cells in vitro. Higher expression levels of CD100 correlate with poor survival in soft tissue sarcoma patients.
Specificity : The mouse monoclonal antibody 133-1C6 recognizes an extracellular epitope of CD100, an approximately 150 kDa (when reduced) semaphorin family member expressed mainly on lymphocytes, NK cells, monocytes/macrophages and granulocytes, but also on some non-hematopoietic cells.

Flow cytometry: The reagent is designed for analysis of human blood cells using 10 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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Anti-Human CD100 PE (Clone : 133-1C6)

Product code: 30-2669
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