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    7. Anti-Human DR5 (Drozitumab) – Dylight® 488

    Anti-Human DR5 (Drozitumab) – Dylight® 488

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    Anti-Human DR5 (Drozitumab) – Dylight® 488

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    Product code: 12-8062

    Clone name : PRO95780
    Clonality : Monoclonal
    Application : Functional Assay
    Reactivity : Human

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    Size
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    100 µg
    $599.00  $479.20 

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    • Product Info
    • Antigen Details
    • Description
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    Amount : 100 µg
    Isotype : Human IgG1lambda
    Content : Concentration : 0.2 mg/ml
    This DyLight® 488 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
    Storage condition : This DyLight® 488 conjugate is stable when stored at 2-8°C. Do not freeze.
    Alternative Name : DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5
    Immunogen Information : DR5 scFv

    Expression Host : HEK-293

    This non-therapeutic biosimilar antibody uses the same variable region sequence as the therapeutic antibody Drozitumab. Clone PRO95780 recognizes human death receptor 5 (DR5). This product is for research use only.
    Drozitumab is a monoclonal antibody that specifically binds to human DR5. DR5 is expressed in a variety of solid tumors and hematologic malignancies, which are characteristically resistant to apoptosis. Drozitumab is a proapoptotic receptor agonists (PARA) that induces apoptosis in a variety of human cancer cell lines and xenograft models, both alone and in tandem with other antineoplastic agents.1 Apoptosis of cancer cells triggered by the activation of DR5, occurs without affecting most normal cell types. Anti-Human DR5 (Drozitumab) utilizes the same variable regions from the therapeutic antibody Drozitumab making it ideal for research projects.

    The suggested concentration for Drozitumab biosimilar antibody for staining cells in flow cytometry is <= 1.0 µg per 106 cells in a volume of 100 µl. Titration of the reagent is recommended for optimal performance for each application.

    For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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    Anti-Human DR5 (Drozitumab) – Dylight® 488

    Product code: 12-8062
    *specify in mg or ml

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