Anti-Mouse CD16/CD32 FITC (Clone : 93)
Figure 1 : Flow cytometry surface staining pattern of murine splenocyte suspension stained using anti-mouse CD16/32 (93) FITC antibody (concentration in sample 15 µg/ml).
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| Amount : | 0.1 mg |
| Isotype : | Rat IgG2a lambda |
| Purification : | Purified by protein-A affinity chromatography |
| Content : | 0.5 mg/ml Formulation : Phosphate buffered saline (PBS) solution with 15 mM sodium azide |
| Storage condition : | Store at 2-8°C. Do not freeze. |
| Gene : | Fcgr2, Fcgr3 |
| Gene ID : | 14130 |
| Alternative Name : | CD16, CD32, FcgammaRIII, FCgammaRII, FCGR3, FCGR2, |
| Immunogen Information : | Murine pre-B cells |
CD16 (FcgammaRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Unlike human, the murine protein is expressed only as a transmembrane isoform. Also CD32 (FcgammaRII) is a low affinity receptor for IgG, but its affinity is lower than that of CD16. These receptors are expressed on monocytes/macrophages, NK cells, granulocytes, mast cells, dendritic cells, and B cells. Their role is to mediate adaptive immune responses through binding the antibody-antigen immunocomplexes, but their effect on the particular cell differs according to the cell type.
Specificity : The rat monoclonal antibody 93 recognizes a common extracellular epitope of murine CD16 (FcgammaRIII) and CD32 (FcgammaRII), the low affinity receptors for IgG.
Specificity : The rat monoclonal antibody 93 recognizes a common extracellular epitope of murine CD16 (FcgammaRIII) and CD32 (FcgammaRII), the low affinity receptors for IgG.
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