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    7. Anti-Mouse CD8b Antibody (Clone : H35-17.2)

    Anti-Mouse CD8b Antibody (Clone : H35-17.2)

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    Figure 1 : Flow cytometry analysis (surface staining) of murine splenocytes using anti-CD8b (H35-17.2) purified, DAR-APC.

    Anti-Mouse CD8b Antibody (Clone : H35-17.2)

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    Product code: 30-2541

    Clone name : H35-17.2
    Clonality : Monoclonal
    Application : IP, FACS , IHC(F)
    Reactivity : Mouse

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    0.1 mg
    $364.00  $291.20 

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    • Product Info
    • Antigen Details
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    Format : Purified
    Amount : 0.1 mg
    Isotype : Rat IgG2b kappa
    Purification : Purified by protein-A affinity chromatography
    Content : 1 mg/ml
    Formulation : Phosphate buffered saline (PBS) solution with 15 mM sodium azide
    Storage condition : Store at 2-8°C. Do not freeze.
    Gene : Cd8b
    Gene ID : 12526
    Alternative Name : Ly-3, Ly-C, Lyt-3
    Immunogen Information : Mouse CD8b
    The CD8b (CD8 beta) subunit of CD8 T cell coreceptor is expressed in CD8 alpha/beta heterodimers on majority of MHC I-restricted conventional T cells and thymocytes and in CD8 alpha/alpha homodimers on subsets of memory T cells, intraepithelial lymphocytes, NK cells, macrophages, mast cells, and dendritic cells. Regulation of CD8 beta level on T cell surface seems to be an important mechanism to control their effector function. Assembly of CD8 alpha/beta but not alpha/alpha dimers is connected with formation or localization to the lipid rafts. Recruiting triggered TCR complexes to these membrane microdomains as well as affinity of TCR to MHC I is modulated by CD8, thereby affecting the functional diversity of the TCR signaling.
    Specificity : The rat monoclonal antibody H35-17.2 recognizes an extracellular epitope of mouse CD8b, the 32-34 kDa beta chain of the CD8 coreceptor, expressed on cytotoxic T cells and thymocytes.
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    Anti-Mouse CD8b Antibody (Clone : H35-17.2)

    Product code: 30-2541
    *specify in mg or ml

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