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  7. Anti-MTAP (Tumor Suppressor Marker) Monoclonal Antibody(Clone: rMTAP/1813)

Anti-MTAP (Tumor Suppressor Marker) Monoclonal Antibody(Clone: rMTAP/1813)

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Fig. 1: Formalin-fixed, paraffin-embedded human Kidney stained with MTAP Recombinant Mouse Monoclonal Antibody (rMTAP/1813).

Anti-MTAP (Tumor Suppressor Marker) Monoclonal Antibody(Clone: rMTAP/1813)
Anti-MTAP (Tumor Suppressor Marker) Monoclonal Antibody(Clone: rMTAP/1813)
Anti-MTAP (Tumor Suppressor Marker) Monoclonal Antibody(Clone: rMTAP/1813)

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Fig. 1: Formalin-fixed, paraffin-embedded human Kidney stained with MTAP Recombinant Mouse Monoclonal Antibody (rMTAP/1813).
Fig. 2: Formalin-fixed, paraffin-embedded human Kidney stained with MTAP Recombinant Mouse Monoclonal Antibody (rMTAP/1813).
Fig. 3: SDS-PAGE Analysis Purified MTAP Recombinant Mouse Monoclonal Antibody (rMTAP/1813). Confirmation of Purity and Integrity of Antibody.

Product code: 36-2805

Clone name : rMTAP/1813
Clonality : Monoclonal
Application : IHC
Reactivity : Human

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  •  100 µg

  • $199.00 

  • $459.00 

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  • Product Info
  • Antigen Details
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Amount : 100 µg
Isotype : Mouse IgG1, kappa
Content : 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition : Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Gene : MTAP
Gene ID : 4507
Uniprot ID : Q13126
Alternative Name : BDMF; DMSFH; DMSMFH; Epididymis luminal protein 249; HEL249; LGMBF; MeSAdo phosphorylase; Methylthioadenosine phosphorylase; MSAP; MTA phosphorylase; MTAPase; S-methyl-5''-thioadenosine phosphorylase
Immunogen Information : Recombinant human MTAP protein fragment (aa97-196) (exact sequence is proprietary)
Recognizes a protein of 31kDa, which is identified as MTAP (5'-deoxy-5'-methylthioadenosine phosphorylase). It catalyzes the reversible phosphorolysis of methylthioadenosine, which is important in polyamine metabolism and for the salvage of adenine and methionine. The gene encoding MTAP is linked to the tumor suppressor gene, p16INK4A. Deficient levels of MTAP can occur in cancers primarily throµgh co-deletion of the MTAP gene and the p16INK4A gene. Cells expressing MTAP and possessing adenine salvage pathway activity may be less susceptible to malignancy due to growth-inhibitory actions of agents (e.g. antifolates), whose mechanism of action, in part, involves this de novo purine pathway.

Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT),(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0 for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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Anti-MTAP (Tumor Suppressor Marker) Monoclonal Antibody(Clone: rMTAP/1813)

Product code: 36-2805
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