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    7. Anti-Rat CD8b Low Endotoxin Antibody (Clone : 341)

    Anti-Rat CD8b Low Endotoxin Antibody (Clone : 341)

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    Anti-Rat CD8b Low Endotoxin Antibody (Clone : 341)

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    Product code: 30-2542

    Clone name : 341
    Clonality : Monoclonal
    Application : FACS , WB, Functional Assay, IP, IHC(F)
    Reactivity : Rat

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    0.1 mg
    $364.00  $291.20 

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    • Product Info
    • Antigen Details
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    Format : Low Endotoxin
    Amount : 0.1 mg
    Isotype : Mouse IgG1 kappa
    Purification : Purified by protein-A affinity chromatography
    Content : 1 mg/ml
    Formulation : Low endotoxin azide free phosphate buffered saline (PBS) solution, 0.2 µm filter sterilized. Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
    Storage condition : Store at 2-8°C. Do not freeze.
    Gene : CD8b
    Gene ID : 926
    Alternative Name : Ly-3, Ly-C, Lyt-3,CD8b molecule
    Immunogen Information : CD8 positive Wistar rat splenic T cell hybridomas
    The CD8b (CD8 beta) subunit of CD8 T cell coreceptor is expressed in CD8 alpha/beta heterodimers on majority of MHC I-restricted conventional T cells and thymocytes and in CD8 alpha/alpha homodimers on subsets of memory T cells, intraepithelial lymphocytes, NK cells, macrophages, mast cells, and dendritic cells. Regulation of CD8 beta level on T cell surface seems to be an important mechanism to control their effector function. Assembly of CD8 alpha/beta but not alpha/alpha dimers is connected with formation or localization to the lipid rafts. Recruiting triggered TCR complexes to these membrane microdomains as well as affinity of TCR to MHC I is modulated by CD8, thereby affecting the functional diversity of the TCR signaling.
    Specificity : The mouse monoclonal antibody 341 (also known as 34.1) recognizes rat CD8b, the 32-34 kDa beta chain of the CD8 coreceptor (extracellular epitope), expressed on T cell subsets and some other cell types, such as macrophages.
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    Anti-Rat CD8b Low Endotoxin Antibody (Clone : 341)

    Product code: 30-2542
    *specify in mg or ml

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