Anti-TACSTD2 / TROP2 (Epithelial Marker) Monoclonal Antibody(Clone: TACSTD2/2151)
|Amount :||100 µg|
|Isotype :||Mouse IgG2b, kappa|
|Content :||200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.|
|Storage condition :||Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.|
|Gene ID :||4070|
|Uniprot ID :||P09758|
|Alternative Name :||Cell surface glycoprotein Trop-2;Membrane Component Chromosome 1, Surface Marker 1 (M1S1);Pancreatic Carcinoma Marker Protein GA733-1;TROP2;Tumor-Associated Calcium Signal Transducer 2 (TACSTD2)|
|Immunogen Information :||Recombinant fragment of human TACSTD2 protein (around aa 31-274) (exact sequence is proprietary)|
TACSTD2is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thyroglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. It plays a role intransducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells.
Western Blot (1-2ug/ml); ,Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),
For Research Use Only. Not for use in diagnostic/therapeutics procedures.