Fig. 1: Formalin-fixed, paraffin-embedded human Placenta stained with TIMP2 Rabbit Recombinant Monoclonal Antibody (TIMP2/2488R).
Roll over image to zoom in
Product code: 36-3263
| Clone name : | TIMP2/2488R |
| Application : | IHC |
| Reactivity : | Human, Mouse, Rat, Guinea Pig, Rabbit, Bovin |
Shipping Info:
For estimated delivery dates, please contact us at support@abeomics.com
| Gene : | TIMP2 |
| Gene ID : | 7077 |
| Uniprot ID : | P16035 |
| Alternative Name : | Metalloproteinase inhibitor 2; TIMP metallopeptidase inhibitor 2; TIMP-2; TIMP2; Tissue Inhibitor of Metalloproteinase 2 |
| Amount : | 100 µg |
| Isotype : | Rabbit IgG |
| Immunogen Information : | A synthetic peptide from the N-terminus of human TIMP2 protein (aa56-66) (DSGNDIYGNPI) |
It recognizes a protein of 21kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
| Content : | 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Storage condition : | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. |
Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
