Abeomics Logo
  • (0) Items
    • Items | total: $0.00 (0)
    • Your shopping cart is empty!

Abeomics Logo

Better Reagents, Better Assays™

  • Account
    • Login
    • Address Book
    • My Order
    • My Wish List
    • Open a New Ticket
  • (0) Items
    • Your shopping cart is empty!

  • About us
  • Products
      • Antibodies
        • TLR and Innate Immunity
        • Apoptosis
        • Immunology
        • DNA methylation and Repair
        • Cell Signalling
        • Infectious Diseases
        • NF-kB Pathway
        • Cancer Marker
        • Loading Controls
        • Stem Cells
        • Development and Differentiation
        • Isotype Controls
        • Secondary Antibodies
        • Tag Antibodies
        • Miscellaneous
      • recmAb™
        • Recombinant Biosimilar Antibodies
        • Recombinant Rabbit Antibodies
        • Recombinant Mouse Antibodies
        • Recombinant Goat Antibodies
      • Cell Lines
        • Primary Cells
        • Reporter Cell Lines
        • Stable Cell Lines
      • Immune-Check Point
      • Kits and Reagents
        • ELISA Kits
        • Apoptosis Detection kits
        • Luciferase reporter assay kits
        • Flowcytometry staining kits
        • Cell dissociation solutions
        • Western Blot membranes (Quick blots/ Q Blots)
      • Tissue Microarray
      • Ligands and Inhibitors
        • Peptide Inhibitors
        • TLR Ligands
        • Caspase Inhibitors
      • Recombinant Proteins
  • Pathways
      • All-Pathways

        View all pathways

      • interactive-pathways

        View all interactive pathways

  • Custom Service
    • Drug Discovery Screening Services
    • Stable Cell Line Development
    • Protein Production
    • Custom Antibody Development
  • Quick order
    • + Add More..

  • Support
  • Contact us
  • Distributors
  1. Catalog
  2. /
  3. Antibodies
  4. /
  5. Cancer Marker
  6. /
  7. 36-3149

Anti-VISTA / B7-H5 / VSIR (Negative Regulator of Immune Response) Monoclonal Antibody(Clone: VISTA/3007)

Share:
Anti-VISTA / B7-H5 / VSIR (Negative Regulator of Immune Response) Monoclonal Antibody(Clone: VISTA/3007)

Fig. 1: Formalin-fixed, paraffin-embedded human Placenta stained with VISTA Monospecific Mouse Monoclonal Antibody (VISTA/3007).

Anti-VISTA / B7-H5 / VSIR (Negative Regulator of Immune Response) Monoclonal Antibody(Clone: VISTA/3007)
Anti-VISTA / B7-H5 / VSIR (Negative Regulator of Immune Response) Monoclonal Antibody(Clone: VISTA/3007)
Anti-VISTA / B7-H5 / VSIR (Negative Regulator of Immune Response) Monoclonal Antibody(Clone: VISTA/3007)
Anti-VISTA / B7-H5 / VSIR (Negative Regulator of Immune Response) Monoclonal Antibody(Clone: VISTA/3007)

Roll over image to zoom in

Fig. 1: Formalin-fixed, paraffin-embedded human Placenta stained with VISTA Monospecific Mouse Monoclonal Antibody (VISTA/3007).
   
Fig. 1: Formalin-fixed, paraffin-embedded human Placenta stained with VISTA Monospecific Mouse Monoclonal Antibody (VISTA/3007).
Fig. 2: Formalin-fixed, paraffin-embedded human SqCC stained with VISTA Monospecific Mouse Monoclonal Antibody (VISTA/3007).
Fig. 3: SDS-PAGE Analysis Purified VISTA Monospecific Mouse Monoclonal Antibody (VISTA/3007). Confirmation of Integrity and Purity of Antibody.
Fig. 4: Analysis of Protein Array containing more than 19,000 full-length human proteins using VISTA Monospecific Mouse Monoclonal Antibody (VISTA/3007). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Product code: 36-3149

Clone name : VISTA/3007
Application : ELISA, IHC
Reactivity : Human

Shipping Info:

For estimated delivery dates, please contact us at support@abeomics.com

Download TDS MSDS
Write a review for this product on BioCompare
Get $20 gift card from Amazon
Size
Price

Available Pack Size(s)

  •   20 µg

  •  100 µg

  • $199.00 

  • $429.00 

Add to Wish List

Bulk Order

Shipping Info:

For estimated delivery dates, please contact us at support@abeomics.com

Download TDS MSDS

  • Antigen Details
  • Description
  • Product Info
  • Application Note
  • Review   (0)
Gene : VSIR
Gene ID : 64115
Uniprot ID : Q9H7M9
Alternative Name : B7H5; DD1alpha; GI24; PD-1H; PDCD1 homolog; Platelet receptor Gi24; PP2135; Stress-induced secreted protein 1 (SISP1); V domain Ig suppressor of T cell activation (VISTA); V Set Immuno-Regulatory Receptor
Amount : 100 µg
Isotype : Mouse IgG2b, kappa
Immunogen Information : Recombinant full-length human VISTA protein
VISTA / GI24 is a transmembrane protein expressed in bone, on embryonic stem cells (ESCs), and on tumor cell surfaces. On ESC s, Gi24 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state. On tumor cells, Gi24 both promotes MT1-MMP expression and activity and serves as a substrate for MT1-MMP. This increases the potential for cell motility. Mature human Gi24 contains a 162aa extracellular region with one V-type Ig-like domain and a 96aa cytoplasmic domain. Human Gi24 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30kDa extracellular fragment plus a 25-30kDa membrane-bound fragment. VISTA is a negative checkpoint regulator and is expressed on myeloid cells, T-cells and human TILs (tumor infiltrating lymphocytes) on MDSCs (myeloid-derived suppressor cells) in the TME (tumor microenvironment). It is very likely both a ligand and receptor and is a promising target for cancer immunotherapy.
Content : 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition : Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.

ELISA (For coating, order antibody without BSA);Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

There are currently no product reviews
Write a review on this product!

Customers who purchased this product also purchased

Anti-BAP1 (BRCA1 Associated Protein 1) Monoclonal Antibody(Clone: BAP1/2431)

Anti-BAP1 (BRCA1 Associated Pr...

details-Anti-BAP1 (BRCA1 Associated Protein 1) Monoclonal Antibody(Clone: BAP1/2431)
Anti-CD4 (T-Helper/Inducer Cell Marker) Monoclonal Antibody(Clone: CD4/3027)

Anti-CD4 (T-Helper/Inducer Cel...

details-Anti-CD4 (T-Helper/Inducer Cell Marker) Monoclonal Antibody(Clone: CD4/3027)
Anti-p63 (Squamous, Basal & Myoepithelial Cell Marker) Monoclonal Antibody(Clone: TP63/2427)

Anti-p63 (Squamous, Basal & My...

details-Anti-p63 (Squamous, Basal & Myoepithelial Cell Marker) Monoclonal Antibody(Clone: TP63/2427)
Anti-Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) Monoclonal Antibody(Clone: AE-1)

Anti-Cytokeratin, Acidic (Type...

details-Anti-Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) Monoclonal Antibody(Clone: AE-1)
Human PD-L1 Recombinant Fc fusion Protein  (Active)

Human PD-L1 Recombinant Fc fus...

details-Human PD-L1 Recombinant Fc fusion Protein  (Active)
Anti-Uroplakin 1B (Urothelial Differentiation Marker) Monoclonal Antibody(Clone: UPK1B/3102)

Anti-Uroplakin 1B (Urothelial ...

details-Anti-Uroplakin 1B (Urothelial Differentiation Marker) Monoclonal Antibody(Clone: UPK1B/3102)
Anti-CD284 (Toll-Like Receptor 4) Monoclonal Antibody(Clone: TLR4/230)

Anti-CD284 (Toll-Like Receptor...

details-Anti-CD284 (Toll-Like Receptor 4) Monoclonal Antibody(Clone: TLR4/230)
Anti-CD84 / SLAMF5 Monoclonal Antibody(Clone: 152-1D5)

Anti-CD84 / SLAMF5 Monoclonal ...

details-Anti-CD84 / SLAMF5 Monoclonal Antibody(Clone: 152-1D5)
Anti-Uroplakin 1B (Urothelial Differentiation Marker) Monoclonal Antibody(Clone: UPK1B/3273)

Anti-Uroplakin 1B (Urothelial ...

details-Anti-Uroplakin 1B (Urothelial Differentiation Marker) Monoclonal Antibody(Clone: UPK1B/3273)
Anti-CD28 Monoclonal Antibody(Clone: C28/74)

Anti-CD28 Monoclonal Antibody(...

details-Anti-CD28 Monoclonal Antibody(Clone: C28/74)
Anti-FITC (Fluorescein Isothiocyanate) Monoclonal Antibody(Clone: SPM395)

Anti-FITC (Fluorescein Isothio...

details-Anti-FITC (Fluorescein Isothiocyanate) Monoclonal Antibody(Clone: SPM395)
Anti-PD-L2 / PDCD1LG2 / CD273 Monoclonal Antibody(Clone: PDL2/1850)

Anti-PD-L2 / PDCD1LG2 / CD273 ...

details-Anti-PD-L2 / PDCD1LG2 / CD273 Monoclonal Antibody(Clone: PDL2/1850)
Anti-Melanoma Associated Antigen (MAA) Monoclonal Antibody(Clone: MAA/1414)

Anti-Melanoma Associated Antig...

details-Anti-Melanoma Associated Antigen (MAA) Monoclonal Antibody(Clone: MAA/1414)
Anti-TIMP2 (Tissue Inhibitor of Metalloproteinase 2) Monoclonal Antibody(Clone: TIMP2/2044)

Anti-TIMP2 (Tissue Inhibitor o...

details-Anti-TIMP2 (Tissue Inhibitor of Metalloproteinase 2) Monoclonal Antibody(Clone: TIMP2/2044)

Most viewed Products

Recombinant Human Thioredoxin-Like 4A

Recombinant Human Thioredoxin-Like ...

details-Recombinant Human Thioredoxin-Like 4A
Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)

Monoclonal antibody to Human PD-L1 ...

details-Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)
Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)

Monoclonal Antibody to Caspase-3 (P...

details-Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)
Polyclonal Antibody to Beta actin

Polyclonal Antibody to Beta actin

details-Polyclonal Antibody to Beta actin
Monoclonal Antibody to GAPDH (Clone: ABM22C5)

Monoclonal Antibody to GAPDH (Clone...

details-Monoclonal Antibody to GAPDH (Clone: ABM22C5)
Monoclonal antibody to B7-H4 (Clone: ABM53A6)

Monoclonal antibody to B7-H4 (Clone...

details-Monoclonal antibody to B7-H4 (Clone: ABM53A6)
Polyclonal Antibody to Beta Tubulin

Polyclonal Antibody to Beta Tubulin

details-Polyclonal Antibody to Beta Tubulin
Peroxidase conjugated Goat anti Mouse IgG (H+L)

Peroxidase conjugated Goat anti Mou...

details-Peroxidase conjugated Goat anti Mouse IgG (H+L)
Monoclonal Antibody to EpCAM (CD326) Cytoplasmic Domain (Clone: ABM2C92)

Monoclonal Antibody to EpCAM (CD326...

details-Monoclonal Antibody to EpCAM (CD326) Cytoplasmic Domain (Clone: ABM2C92)
Polyclonal antibody to APAF-1

Polyclonal antibody to APAF-1

details-Polyclonal antibody to APAF-1

Related Products

Anti-HLA-B (MHC Class I) Monoclonal Antibody(Clone: SPM420)

Anti-HLA-B (MHC Class I) Monoclonal Antibody(Clone: SPM420)

Anti-HPV-16 (Human Papilloma Virus 16) Monoclonal Antibody(Clone: HPV16/2058R)

Anti-HPV-16 (Human Papilloma Virus 16) Monoclonal Antibody(Clone: HPV16/2058R)

Anti-Connexin 32 (Gap Junction Protein) Monoclonal Antibody(Clone: R5.21C)

Anti-Connexin 32 (Gap Junction Protein) Monoclonal Antibody(Clone: R5.21C)

New Products

Monoclonal Antibody to Human PD-L1 (Clone: ABM4E54) (BSA/AZIDE Free)

Monoclonal Antibody to Human PD-L1 (Clone: ABM4E54) (BSA/AZIDE Free)

close

Please Login to write a Review !!


close

Anti-VISTA / B7-H5 / VSIR (Negative Regulator of Immune Response) Monoclonal Antibody(Clone: VISTA/3007)

Product code: 36-3149
*specify in mg or ml

Abeomics Logo

Better Reagents, Better Assays™

Tel : 858-263-4982

Fax : 858-247-7052

Email : support@abeomics.com

Connect with Us

  • Facebook
  • Twitter
  • Linkedin
  • YouTube

Products

  • Antibodies
  • recmAb™
  • Cell Lines
  • Immune-Check Point
  • Kits and Reagents
  • Tissue Microarray
  • Ligands and Inhibitors
  • Recombinant Proteins

Services

  • Drug Discovery Screening Services
  • Stable Cell Line Development
  • Protein Production
  • Custom Antibody Development

Quick order

+ Add More..

Newsletter

© 2019 Abeomics. All rights reserved.
  • Blog
  • Sitemap
  • Terms
  • Privacy Policy
  • Legal
  • Email unsubscribe

Item added to cart successfully

No cart item available
Continue shopping View Cart