BTLA Stable Cell Line-CHO-K1-Human
Figure 1: FACS analysis of BTLA expression in CHO-K1/BTLA cells.
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| Amount : | 2 vials |
| Content : | Each Vial contains cells in 95% complete growth medium+ 5% DMSO |
| Storage condition : | Immediately upon receipt, store in liquid nitrogen. |
| Alternative Name : | BTLA1; CD272 |
The B and T lymphocyte attenuator (BTLA) is an Ig super family protein with an intermediate type Ig fold in the ectodomain and an ITIM inhibitory signaling domain in the cytosol. BTLA interacts with the herpesvirus entry mediator (HVEM; TNFRSF14), a TNFR super family member. Engagement of BTLA by HVEM, induces tyrosine phosphorylation of the ITIM motifs in the cytoplasmic tail of BTLA, allowing the recruitment of the phosphatases SHP-1 and SHP-2, which attenuate signaling.
Application: Screen for antibodies through Flow Cytometry, Immunocytochemistry or Western blotting. Culture Medium: F12K, 10% FBS, 600 µg/ml G418
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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