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DNA methylation and Repair

DNA methylation is an epigenetic process that involves the addition of methyl groups to the DNA molecule at many different sites and alters the gene expression by producing lethal and mutagenic lesions. DNA methylation regulates gene expression by the recruitment of proteins involved in gene expression or inhibiting the transcription factors that bind to the DNA. Epigenetic mechanisms like DNA methylation are reversible processes and their inhibition plays a role in the repair of double-strand breaks, the most detrimental type of DNA damage. When damaged DNA is repaired, epigenetic markers are also reconstructed. DNA methylation is believed to be more resilient than other epigenetic markers and aids in maintaining alterations in gene expression. A DNA methylation antibody aids researchers in their understanding of DNA methylation and how illnesses, cell cycle control, and embryonic development are affected by it.

Abeomics Inc. offers well-characterized DNA methylation antibodies that may help scientists and researchers better understand the role of aberrant DNA methylation in diseases like cancer, atherosclerosis, cardiovascular diseases, and nervous disorders. Major methylation antibodies include DNMT3b, DNMT3a, MBD1, MLH1, PMS2 etc. 

DNA methylation and Repair

(87 RESULTS)
Displaying 51 to 60 (of 87 products)
Phospho-Histone H2A.X (Ser139) (Clone: 1E4) rabbit mAb SureLight 488 conjugate
 
Catalogue No.:12-4216
Clone:HisH2AXS139-1E4
Clonality: Monoclonal
Application: FACS
Format: Conjugated
Reactivity: Human, Mouse
Conjugate: SureLight 488

10 Tests - $392.00 

100 Tests - $629.00 

Details-Phospho-Histone H2A.X (Ser139) (Clone: 1E4) rabbit mAb SureLight 488 conjugate
Cleaved PARP (Asp214) (Clone: H8) rabbit mAb
 
Catalogue No.:12-4264
Clone:PARP-H8
Clonality: Monoclonal
Application: FACS,WB
Format: Purified
Reactivity: Human
Conjugate: Unconjugated

20 µl - $482.00 

200 µl - $837.00 

Details-Cleaved PARP (Asp214) (Clone: H8) rabbit mAb
Cleaved PARP (Asp214) (Clone: H8) rabbit mAb PE conjugate
 
Catalogue No.:12-4265
Clone:PARP-H8
Clonality: Monoclonal
Application: FACS
Format: Conjugated
Reactivity: Human
Conjugate: PE

10 Tests - $392.00 

100 Tests - $629.00 

Details-Cleaved PARP (Asp214) (Clone: H8) rabbit mAb PE conjugate
Cleaved PARP (Asp214) (Clone: H8) rabbit mAb FITC conjugate
 
Catalogue No.:12-4266
Clone:PARP-H8
Clonality: Monoclonal
Application: FACS
Format: Conjugated
Reactivity: Human
Conjugate: FITC

10 Tests - $392.00 

100 Tests - $629.00 

Details-Cleaved PARP (Asp214) (Clone: H8) rabbit mAb FITC conjugate
Cleaved PARP (Asp214) (Clone: H8) rabbit mAb APC conjugate
 
Catalogue No.:12-4267
Clone:PARP-H8
Clonality: Monoclonal
Application: FACS
Format: Conjugated
Reactivity: Human
Conjugate: APC

10 Tests - $392.00 

100 Tests - $629.00 

Details-Cleaved PARP (Asp214) (Clone: H8) rabbit mAb APC conjugate
Anti-HDAC6 Antibody (Clone : 2H3)
 
Catalogue No.:30-2523
Clone:2H3
Clonality: Monoclonal
Application: ICC, ELISA
Format: Purified
Reactivity: Human

0.1 mg - $398.00 

Details-Anti-HDAC6 Antibody (Clone : 2H3)
Anti-HDAC6 Antibody (Clone : 3D2)
 
Catalogue No.:30-2524
Clone:3D2
Clonality: Monoclonal
Application: WB, ICC, ELISA
Format: Purified
Reactivity: Human

0.1 mg - $398.00 

Details-Anti-HDAC6 Antibody (Clone : 3D2)
Anti-HDAC6 Antibody (Clone : 159)
 
Catalogue No.:30-2525
Clone:159
Clonality: Monoclonal
Application: WB, ICC, ELISA, FACS
Format: Purified
Reactivity: Human

0.1 mg - $398.00 

Details-Anti-HDAC6 Antibody (Clone : 159)
Anti-HDAC6 Antibody (Clone : 178)
 
Catalogue No.:30-2526
Clone:178
Clonality: Monoclonal
Application: ICC, ELISA, IP
Format: Purified
Reactivity: Human

0.1 mg - $398.00 

Details-Anti-HDAC6 Antibody (Clone : 178)
Anti-HDAC6 Antibody (Clone : 236)
 
Catalogue No.:30-2527
Clone:236
Clonality: Monoclonal
Application: IP
Format: Purified
Reactivity: Human

0.1 mg - $398.00 

Details-Anti-HDAC6 Antibody (Clone : 236)
Displaying 51 to 60 (of 87 products)

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