SARS-CoV-2 Spike S1 Mutant Sampler Set
Figure-1: Recombinant SARS-CoV-2 Spike S1 wild type (WT), N439K, D614G, K417N/E484K/N501Y and S13l/W152C/L452R mutant proteins were run on a 4-20% SDS-PAGE gel followed by Coomassie blue staining.
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| Amount : | 25 μg X 5 |
| Purification : | >95% by SDS-PAGE. |
| Content : | PBS and 10% Glycerol. |
| Storage condition : | SARS-CoV-2 Spike S1 Mutant Sampler Set is shipped on ice packs. Upon arrival, store at -20°C. Do not freeze-thaw multiple times. |
| AA sequence : | The target proteins are expressed in CHO-K1 cells with sequence (AA 14-683) of SARS-CoV-2/COVID-19 Spike S1 fused with a 10xHis tag in C-Terminal. |
This SARS-CoV-2 Spike S1 Mutant Sampler Set contains: wild type Spike S1 protein (Cat. No. 21-1008), D614G mutant (Cat. No. 21-1009), N439K mutant (Cat. No. 21-1012), K417N/E484K/N501Y (South African) mutant (Cat. No. 21-1017), and S13l/W152C/L452R (Southern California) mutant (Cat. No. 21-1018) recombinant proteins expressed in CHO-K1.
The spike protein S1 subunit of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S1 mediates this interaction. The S protein plays key parts in the induction of neutralizing antibodies and T-cell responses, as well as protective immunity.
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