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  7. G alpha 15 Stable Cell Line-GLP1-CHO-K1-Human(Currently Unavailable)

G alpha 15 Stable Cell Line-GLP1-CHO-K1-Human(Currently Unavailable)

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Figure 1: Concentration-dependent stimulation of intracellular calcium mobilization by GLP-1 (7-37) in CHO-K1/GLP1/G alpha 15 cells

G alpha 15 Stable Cell Line-GLP1-CHO-K1-Human(Currently Unavailable)

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Product code: 14-6173ACL

Application : Functional Assay
Reactivity : Human

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Amount : 2 vials
Content : Each Vial contains cells in 45% culture medium, 45% FBS, 10% DMSO
Storage condition : Immediately upon receipt, store in liquid nitrogen.
Alternative Name : Human Recombinant Glucagon-like Peptide 1 Receptor Stable Cell Line
GLP1R binds specifically the glucagon-like peptide-1 (GLP1) and has much lower affinity for related peptides such as the gastric inhibitory polypeptide and glucagon. GLP1R is known to be expressed in pancreatic beta cells. Activated GLP1R stimulates the adenylyl cyclase pathway which results in increased insulin synthesis and release of insulin. Consequently, GLP1R has been suggested as a potential target for the treatment of diabetes. GLP1R is also expressed in the brain where it is involved in the control of appetite. Furthermore, mice which over express GLP1R display improved memory and learning.

Application: Screen for antibodies through Flow Cytometry, Immunocytochemistry or Western blotting.
Culture Medium: Ham's F12, 10% FBS, 200 µg/ml Zeocin, 100 µg/ml Hygromycin B

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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G alpha 15 Stable Cell Line-GLP1-CHO-K1-Human(Currently Unavailable)

Product code: 14-6173ACL
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