Human CFD Protein, hFc Tag
Figure 1.Human CFD Protein, hFc Tag on SDS-PAGE under reducing condition.
Roll over image to zoom in
Shipping Info:
For estimated delivery dates, please contact us at [email protected]
| Amount : | 100 µg |
| Purification : | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Content : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. |
| Storage condition : | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Uniprot ID : | P00746 |
| Alternative Name : | ADIPSIN;ADN;DF;PFD |
Description :Recombinant Human CFD Protein with C-terminal human Fc tag
Background : This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease.
Molecular Characterization: mass of 50.5 kDa after removal of the signal peptide. The apparent molecular mass of CFD-hFc is approximately 55-70 kDa due to glycosylation.
Tag :C-Human Fc Tag
Background : This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease.
Molecular Characterization: mass of 50.5 kDa after removal of the signal peptide. The apparent molecular mass of CFD-hFc is approximately 55-70 kDa due to glycosylation.
Tag :C-Human Fc Tag
|
There are currently no product reviews
|
.png "ACE2/HEK293 Stable Cell Line")
