Abeomics Logo
  • (0) Items
    • Items | total: $0.00 (0)
    • Your shopping cart is empty!

Abeomics Logo

Antibodies & Engineered Cell Lines™

  • Account
    • Login
    • Address Book
    • My Order
    • My Wish List
    • Open a New Ticket
  • (0) Items
    • Your shopping cart is empty!

  • About us
  • Products
      • Antibodies
        • Biosimilars
        • TLR and Innate Immunity
        • Apoptosis
        • Immunology
        • DNA methylation and Repair
        • Cell Signalling
        • Infectious Diseases
        • NF-kB Pathway
        • Cancer Marker
        • Loading Controls
        • Stem Cells
        • Development and Differentiation
        • Isotype Controls
        • Secondary Antibodies
        • Tag Antibodies
        • Miscellaneous
      • Cell Lines
        • Reporter Cell Lines
        • Stable Cell Lines
      • Ligands and Inhibitors
        • Peptide Inhibitors
        • Proteases inhibitors
        • TLR Ligands
        • Caspase Inhibitors
      • Recombinant Proteins
        • Recombinant Proteins
      • Immune-Check Point
      • Kits and Reagents
        • Luciferase reporter assay kits
        • Inhibitor Screening Kit
        • ELISA Kits
        • Molecular Biology Kits
        • Apoptosis Detection kits
        • Flowcytometry staining kits
        • Cell dissociation solutions
        • Western Blot membranes (Quick blots/ Q Blots)
      • Tissue Microarray
      • recmAb™
        • Recombinant Biosimilar Antibodies
        • Recombinant Rabbit Antibodies
        • Recombinant Mouse Antibodies
  • Pathways
      • All-Pathways

        View all pathways

      • interactive-pathways

        View all interactive pathways

  • Custom Service
    • Drug Discovery Screening Services
    • Stable Cell Line Development
    • Protein Production
    • Custom Antibody Development
  • Quick order
    • + Add More..

  • Support
  • Contact us
  • Distributors
  1. Catalog
  2. /
  3. Recombinant Proteins
  4. /
  5. INSR Recombinant Protein

INSR Recombinant Protein

Share:

INSR Recombinant Protein

Roll over image to zoom in

   

Product code: 32-1542

Shipping Info:

For estimated delivery dates, please contact us at support@abeomics.com

Download TDS / Manual
Write a review for this product on BioCompare
Get $20 gift card from Amazon
Size
Price
10 µg
$363.00 

Add to Wish List

Bulk Order

Shipping Info:

For estimated delivery dates, please contact us at support@abeomics.com

Download TDS / Manual

  • Product Info
  • Description
  • Application Note
  • Review   (0)
Amount : 10 µg
Purification : Greater than 95.0% as determined by SDS-PAGE.
Content : INSR was filtered (0.4µm) and lyophilized from 0.5mg/ml in 0.05M phosphate buffer and 0.075M NaCl, pH 7.4.
Storage condition : Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time.
AA sequence : ASHLYPGEVC PGMDIRNNLT RLHELENCSV IEGHLQILLM FKTRPEDFRD LSFPKLIMIT DYLLLFRVYG LESLKDLFPN LTVIRGSRLF FNYALVIFEM VHLKELGLYN LMNITRGSVR IEKNNELCYL ATIDWSRILD SVEDNYIVLN KDDNEECGDI CPGTAKGKTN CPATVINGQF VERCWTHSHC QKVCPTICKS HGCTAEGLCC HSECLGNCSQ PDDPTKCVAC RNFYLDGRCV ETCPPPYYHF QDWRCVNFSF CQDLHHKCKN SRRQGCHQYV IHNNKCIPEC PSGYTMNSSN LLCTPCLGPC PKVCHLLEGE KTIDSVTSAQ ELRGCTVING SLIINIRGGN NLAAELEANL GLIEEISGYL KIRRSYALVS LSFFRKLRLI RGETLEIGNY SFYALDNQNL RQLWDWSKHN LTITQGKLFF HYNPKLCLSE IHKMEEVSGT KGRQERNDIA LKTNGDQASC ENELLKFSYI RTSFDKILLR WEPYWPPDFR DLLGFMLFYK EAPYQNVTEF DGQDACGSNS WTVVDIDPPL RSNDPKSQNH PGWLMRGLKP WTQYAIFVKT LVTFSDERRT YGAKSDIIYV QTDATNPSVP LDPISVSNSS SQIILKWKPP SDPNGNITHY LVFWERQAED SELFELDYCL KGLKLPSRTW SPPFESEDSQ KHNQSEYEDS AGECCSCPKT DSQILKELEE SSFRKTFEDY LHNVVFVPRP SRKRRSLGDV GNVTVAVPTV AAFPNTSSTS VPTSPEEHRP FEKVVNKESL VISGLRHFTG YRIELQACNQ DTPEERCSVA AYVSARTMPE AKADDIVGPV THEIFENNVV HLMWQEPKEP NGLIVLYEVS YRRYGDEELH LCVSRKHFAL ERGCRLRGLS PGNYSVRIRA TSLAGNGSWT EPTYFYVTDY LDVPSNIAKK LHHHHHH.
Alternative Name : Insulin receptor, IR, EC 2.7.10.1, CD220, INSR, HHF5.

Source : HEK 293. Insulin Receptor Human Recombinant produced in HEK cells is a single, glycosylated, polypeptide chain (aa 28-944 of the short isoform- HIR-A, Uniprot accession # P06213-2 which includes the whole subunit alpha and extracellular domain of subunit beta) containing a total of 927 amino acids, having a molecular mass of 105.9kDa (calculated), though it migrates at approximately 160kDa on SDS PAGE, the INSR is fused to a 2 a.a N-terminal linker, a 2 a.a C-terminal linker and fused to a 6 a.a His tag at C-Terminus.The Human INSR is purified by proprietary chromatographic techniques. Insulin Receptor (INSR) is a receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Once the precursor signal peptide is removed, the insulin receptor precursor is post-translationally cleaved into 2 chains (alpha and beta) which are covalently linked. Insulin binding initiates phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates. Each of these phosphorylated proteins function as docking proteins for other signaling proteins which contain Src-homology-2 domains (SH2 domain) that specifically recognize different phosphotyrosines residues, including the p85 regulatory subunit of PI3K and SHP2.

It is recommended to add 200µl deionized water to a working concentration of 0.5mg/ml and let the lyophilized pellet dissolve completely. INSR is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

There are currently no product reviews
Write a review on this product!

Customers who purchased this product also purchased

Bovine Aprotinin Native Protein

Bovine Aprotinin Native Protei...

details-Bovine Aprotinin Native Protein
Recombinant human CXCL12 protein with C-terminal human Fc tag

Recombinant human CXCL12 prote...

details-Recombinant human CXCL12 protein with C-terminal human Fc tag
Anti-CD138 Monoclonal Antibody (Clone:IHC138)-Ready to Use

Anti-CD138 Monoclonal Antibody...

details-Anti-CD138 Monoclonal Antibody (Clone:IHC138)-Ready to Use
Anti-CS1 antibody(DM9), Rabbit mAb

Anti-CS1 antibody(DM9), Rabbit...

details-Anti-CS1 antibody(DM9), Rabbit mAb
Mouse Monoclonal Antibody to IL-8 (Clone : 3B1C10)(Discontinued)

Mouse Monoclonal Antibody to I...

details-Mouse Monoclonal Antibody to IL-8 (Clone : 3B1C10)(Discontinued)
Alkaline phosphatase conjugated Goat anti Rabbit IgG (H+L)

Alkaline phosphatase conjugate...

details-Alkaline phosphatase conjugated Goat anti Rabbit IgG (H+L)
Mouse Monoclonal Antibody to Human RANTES (Clone : 4A10F2)(Discontinued)

Mouse Monoclonal Antibody to H...

details-Mouse Monoclonal Antibody to Human RANTES (Clone : 4A10F2)(Discontinued)
Anti-Cytokeratin 19 Monoclonal Antibody (Clone:IHC019)-Ready to Use

Anti-Cytokeratin 19 Monoclonal...

details-Anti-Cytokeratin 19 Monoclonal Antibody (Clone:IHC019)-Ready to Use
Biotin Conjugated, Anti-alpha-tubulin Monoclonal Antibody (Clone:TU-01)

Biotin Conjugated, Anti-alpha-...

details-Biotin Conjugated, Anti-alpha-tubulin Monoclonal Antibody (Clone:TU-01)
Anti-MSLN antibody(DM72), Rabbit mAb

Anti-MSLN antibody(DM72), Rabb...

details-Anti-MSLN antibody(DM72), Rabbit mAb
Anti-Human CD34 PE-DyLight® 594 (Clone : 4H11[APG])

Anti-Human CD34 PE-DyLight® 5...

details-Anti-Human CD34 PE-DyLight® 594 (Clone : 4H11[APG])
Anti-HSP60 Monoclonal Antibody (Clone : LK1) ATTO 488

Anti-HSP60 Monoclonal Antibody...

details-Anti-HSP60 Monoclonal Antibody (Clone : LK1) ATTO 488
Anti-Human IL-2R alpha (CD25) (Basiliximab) – APC

Anti-Human IL-2R alpha (CD25) ...

details-Anti-Human IL-2R alpha (CD25) (Basiliximab) – APC
Anti-SARS-CoV-2 Spike antibody(DM40), Rabbit mAb

Anti-SARS-CoV-2 Spike antibody...

details-Anti-SARS-CoV-2 Spike antibody(DM40), Rabbit mAb

Most viewed Products

Recombinant Human Thioredoxin-Like 4A

Recombinant Human Thioredoxin-Like ...

details-Recombinant Human Thioredoxin-Like 4A
NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line

NF-kB Leeporter™ Luciferase Repor...

details-NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line
Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)

Monoclonal Antibody to Human IL-1be...

details-Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)
Polyclonal Antibody to Beta actin

Polyclonal Antibody to Beta actin

details-Polyclonal Antibody to Beta actin
Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)

Monoclonal Antibody to Caspase-3 (P...

details-Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)
Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)

Monoclonal antibody to Human PD-L1 ...

details-Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)
Monoclonal Antibody to GAPDH (Clone: ABM22C5)

Monoclonal Antibody to GAPDH (Clone...

details-Monoclonal Antibody to GAPDH (Clone: ABM22C5)
Recombinant Human Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His)

Recombinant Human Indoleamine 2,3-D...

details-Recombinant Human Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His)
Monoclonal antibody to B7-H4 (Clone: ABM53A6)

Monoclonal antibody to B7-H4 (Clone...

details-Monoclonal antibody to B7-H4 (Clone: ABM53A6)
Polyclonal Antibody to Beta Tubulin

Polyclonal Antibody to Beta Tubulin

details-Polyclonal Antibody to Beta Tubulin

Related Products

Recombinant human IL2RA Protein with C-6×His tag

Recombinant human IL2RA Protein with C-6×His tag

Human Neurotrophin-4

Human Neurotrophin-4

Recombinant Human Acyl-Coenzyme A Thioesterase 13/ACOT13 (C-6His)

Recombinant Human Acyl-Coenzyme A Thioesterase 13/ACOT13 (C-6His)

New Products

Anti-Hu CD95 PE-DyLight<sup>®</sup> 594

Anti-Hu CD95 PE-DyLight<sup>®</sup> 594

Biotinylated Human FGL1 (C-Fc-Avi)

Biotinylated Human FGL1 (C-Fc-Avi)

Recombinant Human IL-1RAPL1 (C-Fc)

Recombinant Human IL-1RAPL1 (C-Fc)

close

Please Login to write a Review !!


close

INSR Recombinant Protein

Product code: 32-1542
*specify in mg or ml

Abeomics Logo

Antibodies & Engineered Cell Lines™

Tel : 858-263-4982

Fax : 858-247-7052

Email : support@abeomics.com

Connect with Us

  • Facebook
  • Twitter
  • Linkedin
  • YouTube

Products

  • Antibodies
  • Cell Lines
  • Ligands and Inhibitors
  • Recombinant Proteins
  • Immune-Check Point
  • Kits and Reagents
  • Tissue Microarray
  • recmAb™

Services

  • Drug Discovery Screening Services
  • Stable Cell Line Development
  • Protein Production
  • Custom Antibody Development

Quick order

+ Add More..

Newsletter

Posters and Flyers

© 2023 Abeomics. All rights reserved.
  • Blog
  • Sitemap
  • Terms
  • Privacy Policy
  • Legal
  • Email unsubscribe

Item added to cart successfully

No cart item available
Continue shopping View Cart