Abeomics Logo
  • (0) Items
    • Items | total: $0.00 (0)
    • Your shopping cart is empty!

Abeomics Logo

Antibodies & Engineered Cell Lines™

  • Account
    • Login
    • Address Book
    • My Order
    • My Wish List
    • Open a New Ticket
  • (0) Items
    • Your shopping cart is empty!

  • About us
  • Products
      • Antibodies
        • TLR and Innate Immunity
        • Apoptosis
        • Immunology
        • DNA methylation and Repair
        • Cell Signalling
        • Infectious Diseases
        • NF-kB Pathway
        • Cancer Marker
        • Loading Controls
        • Stem Cells
        • Development and Differentiation
        • Isotype Controls
        • Secondary Antibodies
        • Tag Antibodies
        • Miscellaneous
      • Cell Lines
        • Primary Cells
        • Reporter Cell Lines
        • Stable Cell Lines
      • Ligands and Inhibitors
        • Peptide Inhibitors
        • Proteases inhibitors
        • TLR Ligands
        • Caspase Inhibitors
      • Recombinant Proteins
      • Immune-Check Point
      • Kits and Reagents
        • Luciferase reporter assay kits
        • Inhibitor Screening Kit
        • ELISA Kits
        • Molecular Biology Kits
        • Apoptosis Detection kits
        • Flowcytometry staining kits
        • Cell dissociation solutions
        • Western Blot membranes (Quick blots/ Q Blots)
      • Tissue Microarray
      • recmAb™
        • Recombinant Biosimilar Antibodies
        • Recombinant Rabbit Antibodies
        • Recombinant Mouse Antibodies
  • Pathways
      • All-Pathways

        View all pathways

      • interactive-pathways

        View all interactive pathways

  • Custom Service
    • Drug Discovery Screening Services
    • Stable Cell Line Development
    • Protein Production
    • Custom Antibody Development
  • Quick order
    • + Add More..

  • Support
  • Contact us
  • Distributors
  1. Catalog
  2. /
  3. Antibodies
  4. /
  5. Apoptosis
  6. /
  7. Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12) FITC Conjugated

Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12) FITC Conjugated

Share:

Fig-1:Intracellular FLOW cytometric analysis of Caspase 3 (Clone : ABM1C12) on Jurkat cells using 0.5 ug of antibody. Green represents FITC conjugated IgG1 isotype control (ABEOMICS), red represents FITC conjugated anti-caspase 3 (10-1003-F) antibody.

Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12) FITC Conjugated

Roll over image to zoom in

   

Product code: 10-1003-F

Clone name : ABM1C12
Clonality : Monoclonal
Application : FACS
Reactivity : Human
Conjugate : FITC

Shipping Info:

Order now and get it on Tuesday March 02, 2021

Same day delivery FREE on San Diego area orders placed by 1.00 PM

Local delivery areas

Same-day delivery in San Diego available for the following zip codes:

92121, 92122, 92037, 92117, 92109, 92110, 92101, 92010, 92011, 92009, 92008
Download TDS MSDS
Write a review for this product on BioCompare
Get $20 gift card from Amazon
Size
Price
100 µg
$270.00 

Add to Wish List

Bulk Order

Shipping Info:

Order now and get it on Tuesday March 02, 2021

Same day delivery FREE on San Diego area orders placed by 1.00 PM

Download TDS MSDS

  • Product Info
  • Antigen Details
  • Description
  • Application Note
  • More
  • Review   (0)
Format : Purified
Amount : 100 µg
Isotype : Mouse IgG1 Kappa
Purification : Protein G Chromatography
Content : 25 µg in 125 µl/100 µg in 500 µl Tris and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C, stable for 6 months.
Gene : CASP3
Gene ID : 836
Uniprot ID : P42574
Alternative Name : Casp3, Cpp32
Immunogen Information : Full length recombinant Caspase-3 protein was used as the immunogen for this antibody.

Caspases are a member of the cysteine-aspartic acid protease family. Caspase-3 (31 kDa) is an executionary caspase which directly cleaves and activates poly(ADP-ribose) polymerase (PARP), sterol regulatory element binding proteins (SREBPs) or it can also interact with other caspases like caspase-6, -7 and -9. Increased levels of caspase-3 are involved in Huntington Disease-associated cell death. Caspase-3 is the principal caspase in mediating the cleavage of amyloid-beta 4A precursor protein (APP), which is related with neuronal death in Alzheimer's disease. Like other caspases, caspase-3 is also synthesized as a zymogen procaspase which is activated by specific proteolytic cleavage. High levels of caspase-3 are observed in lung, spleen, heart, liver and kidney, moderate levels in brain and skeletal muscle, and low in testis.

FACS: 0.5-1 µg/10^6

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cytoplasm
Post transnational modification: S-nitrosylated on its catalytic site cysteine in unstimulated human cell lines and denitrosylated upon activation of the Fas apoptotic pathway, associated with an increase in intracellular caspase activity. Fas therefore activates caspase-3 not only by inducing the cleavage of the caspase zymogen to its active subunits, but also by stimulating the denitrosylation of its active site thiol.
Tissue Specificity: Highly expressed in lung, spleen, heart, liver and kidney. Moderate levels in brain and skeletal muscle, and low in testis. Also found in many cell lines, highest expression in cells of the immune system.
BioGrid: 107286. 102 interactions.
There are currently no product reviews
Write a review on this product!

Customers who purchased this product also purchased

Monoclonal Antibody to Human sMD-2 and sMD-2/TLR4 (Clone : 4H1)

Monoclonal Antibody to Human s...

details-Monoclonal Antibody to Human sMD-2 and sMD-2/TLR4 (Clone : 4H1)
Anti-GLUT-1 (Tumor Progression and Mesothelioma Marker) Monoclonal Antibody(Clone: GLUT1/2476)

Anti-GLUT-1 (Tumor Progression...

details-Anti-GLUT-1 (Tumor Progression and Mesothelioma Marker) Monoclonal Antibody(Clone: GLUT1/2476)
G alpha 15 Stable Cell Line-ADORA2B-CHO-K1-Human(Currently Unavailable)

G alpha 15 Stable Cell Line-AD...

details-G alpha 15 Stable Cell Line-ADORA2B-CHO-K1-Human(Currently Unavailable)
Anti-Wilm's Tumor 1 (WT1) (Wilm's Tumor & Mesothelial Marker) Monoclonal Antibody(Clone: rWT1/857)

Anti-Wilm's Tumor 1 (WT1) ...

details-Anti-Wilm's Tumor 1 (WT1) (Wilm's Tumor & Mesothelial Marker) Monoclonal Antibody(Clone: rWT1/857)
ACE2 Antibody

ACE2 Antibody

details-ACE2 Antibody
HVEM Stable Cell Line-CHO-K1-Human(Currently Unavailable)

HVEM Stable Cell Line-CHO-K1-H...

details-HVEM Stable Cell Line-CHO-K1-Human(Currently Unavailable)
PRLHR Stable Cell Line-CHO-K1-Human(Currently Unavailable)

PRLHR Stable Cell Line-CHO-K1-...

details-PRLHR Stable Cell Line-CHO-K1-Human(Currently Unavailable)
Monoclonal Antibody to Human CD23 (Clone: 152-5E5)

Monoclonal Antibody to Human C...

details-Monoclonal Antibody to Human CD23 (Clone: 152-5E5)
Anti-CD80 (B7-1) Monoclonal Antibody(Clone: C80/2776)

Anti-CD80 (B7-1) Monoclonal An...

details-Anti-CD80 (B7-1) Monoclonal Antibody(Clone: C80/2776)
G alpha 15 Stable Cell Line-CCR1-CHO-K1-Human(Currently Unavailable)

G alpha 15 Stable Cell Line-CC...

details-G alpha 15 Stable Cell Line-CCR1-CHO-K1-Human(Currently Unavailable)
G alpha 15 Stable Cell Line-H3-CHO-K1-Human(Currently Unavailable)

G alpha 15 Stable Cell Line-H3...

details-G alpha 15 Stable Cell Line-H3-CHO-K1-Human(Currently Unavailable)
Poly(I).Poly(C), HMW

Poly(I).Poly(C), HMW

details-Poly(I).Poly(C), HMW
Polyclonal Antibody to APG4B

Polyclonal Antibody to APG4B

details-Polyclonal Antibody to APG4B
CD16A 158F Stable Cell Line-CHO-K1-Human(Currently Unavailable)

CD16A 158F Stable Cell Line-CH...

details-CD16A 158F Stable Cell Line-CHO-K1-Human(Currently Unavailable)

Most viewed Products

Recombinant Human Thioredoxin-Like 4A

Recombinant Human Thioredoxin-Like ...

details-Recombinant Human Thioredoxin-Like 4A
Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)

Monoclonal Antibody to Human IL-1be...

details-Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)
Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)

Monoclonal antibody to Human PD-L1 ...

details-Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)
Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)

Monoclonal Antibody to Caspase-3 (P...

details-Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)
Polyclonal Antibody to Beta actin

Polyclonal Antibody to Beta actin

details-Polyclonal Antibody to Beta actin
Monoclonal Antibody to GAPDH (Clone: ABM22C5)

Monoclonal Antibody to GAPDH (Clone...

details-Monoclonal Antibody to GAPDH (Clone: ABM22C5)
Monoclonal antibody to B7-H4 (Clone: ABM53A6)

Monoclonal antibody to B7-H4 (Clone...

details-Monoclonal antibody to B7-H4 (Clone: ABM53A6)
Polyclonal Antibody to Beta Tubulin

Polyclonal Antibody to Beta Tubulin

details-Polyclonal Antibody to Beta Tubulin
NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line

NF-kB Leeporter™ Luciferase Repor...

details-NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line
Peroxidase conjugated Goat anti Mouse IgG (H+L)

Peroxidase conjugated Goat anti Mou...

details-Peroxidase conjugated Goat anti Mouse IgG (H+L)

Related Products

Polyclonal antibody to NLRP2/NALP2 (PAN1)

Polyclonal antibody to NLRP2/NALP2 (PAN1)

Phospho-Akt1 (Ser473) (Clone: C7) rabbit mAb PE conjugate

Phospho-Akt1 (Ser473) (Clone: C7) rabbit mAb PE conjugate

Mouse Monoclonal Antibody to AKT3 (Clone: 154CT4.5.3)(Discontinued)

Mouse Monoclonal Antibody to AKT3 (Clone: 154CT4.5.3)(Discontinued)

New Products

Phospho-MEK1/2 (Ser221) (Clone: D3) rabbit mAb FITC Conjugate

Phospho-MEK1/2 (Ser221) (Clone: D3) rabbit mAb FITC Conjugate

Cleaved PARP (Asp214) (Clone: H8) rabbit mAb PE conjugate

Cleaved PARP (Asp214) (Clone: H8) rabbit mAb PE conjugate

Phospho-S6 Ribosomal Protein (Ser235/236) (Clone: R3A2) rabbit mAb APC conjugate

Phospho-S6 Ribosomal Protein (Ser235/236) (Clone: R3A2) rabbit mAb APC conjugate

close

Please Login to write a Review !!


close

Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12) FITC Conjugated

Product code: 10-1003-F
*specify in mg or ml

Abeomics Logo

Antibodies & Engineered Cell Lines™

Tel : 858-263-4982

Fax : 858-247-7052

Email : support@abeomics.com

Connect with Us

  • Facebook
  • Twitter
  • Linkedin
  • YouTube

Products

  • Antibodies
  • Cell Lines
  • Ligands and Inhibitors
  • Recombinant Proteins
  • Immune-Check Point
  • Kits and Reagents
  • Tissue Microarray
  • recmAb™

Services

  • Drug Discovery Screening Services
  • Stable Cell Line Development
  • Protein Production
  • Custom Antibody Development

Quick order

+ Add More..

Newsletter

Posters and Flyers

© 2021 Abeomics. All rights reserved.
  • Blog
  • Sitemap
  • Terms
  • Privacy Policy
  • Legal
  • Email unsubscribe

Item added to cart successfully

No cart item available
Continue shopping View Cart