Abeomics Logo
  • (0) Items
    • Items | total: $0.00 (0)
    • Your shopping cart is empty!

Abeomics Logo

Antibodies & Engineered Cell Lines™

  • Account
    • Login
    • Address Book
    • My Order
    • My Wish List
    • Open a New Ticket
  • (0) Items
    • Your shopping cart is empty!

  • About us
  • Products
      • Antibodies
        • Biosimilars
        • TLR and Innate Immunity
        • Apoptosis
        • Immunology
        • DNA methylation and Repair
        • Cell Signalling
        • Infectious Diseases
        • NF-kB Pathway
        • Cancer Marker
        • Loading Controls
        • Stem Cells
        • Development and Differentiation
        • Isotype Controls
        • Secondary Antibodies
        • Tag Antibodies
        • Miscellaneous
      • Cell Lines
        • Reporter Cell Lines
        • Stable Cell Lines
      • Ligands and Inhibitors
        • Peptide Inhibitors
        • Proteases inhibitors
        • TLR Ligands
        • Caspase Inhibitors
      • Recombinant Proteins
        • Recombinant Proteins
      • Immune-Check Point
      • Kits and Reagents
        • Other Kits
        • Luciferase reporter assay kits
        • Inhibitor Screening Kit
        • ELISA Kits
        • Molecular Biology Kits
        • Apoptosis Detection kits
        • Flowcytometry staining kits
        • Cell dissociation solutions
        • Western Blot membranes (Quick blots/ Q Blots)
      • Tissue Microarray
      • recmAb™
        • Recombinant Biosimilar Antibodies
        • Recombinant Rabbit Antibodies
        • Recombinant Mouse Antibodies
      • sdMAB ™
        • Shark sdMAB ™
        • Alpaca sdMAB ™
  • Pathways
      • All-Pathways

        View all pathways

      • interactive-pathways

        View all interactive pathways

  • Custom Service
    • Drug Discovery Screening Services
    • Stable Cell Line Development
    • Protein Production
    • Custom Antibody Development
    • Custom Recombinant Antibody Development
  • Quick order
    • + Add More..

  • Support
  • Contact us
  • Distributors
  1. Catalog
  2. /
  3. Antibodies
  4. /
  5. Immunology
  6. /
  7. Mouse Monoclonal Antibody to IL-8 (Clone : 4H8F8)(Discontinued)

Mouse Monoclonal Antibody to IL-8 (Clone : 4H8F8)(Discontinued)

Share:

Figure-1 : Western blot analysis of IL-8 Antibody (Clone: 4H8F8) at 1 µg/ml on human recombinant IL-8 fusion protein, IRDye 800 Conjugated Goat Anti-Mouse IgG was used as Secondry antibody.

Mouse Monoclonal Antibody to IL-8 (Clone : 4H8F8)(Discontinued)
Mouse Monoclonal Antibody to IL-8 (Clone : 4H8F8)(Discontinued)
Mouse Monoclonal Antibody to IL-8 (Clone : 4H8F8)(Discontinued)

Roll over image to zoom in

   
Figure-1 : Western blot analysis of IL-8 Antibody (Clone: 4H8F8) at 1 µg/ml on human recombinant IL-8 fusion protein, IRDye 800 Conjugated Goat Anti-Mouse IgG was used as Secondry antibody.
Figure-2 : Sandwich ELISA analysis of matched antibody pairs using Human IL-8 Antibody  (Clone: 4H8F8)  1) ELISA plate was coated with Human IL-8 Antibody (Clone: 4H8F8) 2) Human recombinant IL-8 protein at appropriate dilution was added into appropriate reaction wells 3) After a period of incubation, HRP conjugated Human IL-8 Antibody (Clone. 2D11C10 , 3D4C3 and  4H7C7) was added followed by proper period of incubation.
Figure-3 : ELISA analysis of Cross reactivity using Human IL-8 Antibody (Clone: 4H8F8).

Product code: 45-1054

Clone name : 4H8F8
Clonality : Monoclonal
Application : ELISA
Reactivity : Human

Shipping Info:

For estimated delivery dates, please contact us at support@abeomics.com

Download TDS MSDS
Write a review for this product on BioCompare
Get $20 gift card from Amazon

Shipping Info:

For estimated delivery dates, please contact us at support@abeomics.com

Download TDS MSDS

  • Product Info
  • Antigen Details
  • Description
  • Application Note
  • More
  • Review   (0)
Format : Purified
Amount : 40 µg
Isotype : Mouse IgG1, κ
Purification : Protein A chromatography
Content : 0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide.
Storage condition : The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
Gene : CXCL8
Gene ID : 3576
Uniprot ID : P10145
Alternative Name : C-X-C motif chemokine 8, Chemokine (C-X-C motif) ligand 8, Emoctakin, Granulocyte chemotactic protein 1, GCP-1, Monocyte-derived neutrophil chemotactic factor, MDNCF, Monocyte-derived neutrophil-activating peptide, MONAP, Neutrophil-activating protein 1, NAP-1, Protein 3-10C T-cell chemotactic factor
Immunogen Information : Amino acids sequence: MTSKLAVALL AAFLISAALC EGAVLPRSAK ELRCQCIKTY SKPFHPKFIK ELRVIESGPH CANTEIIVKL SDGRELCLDP KENWVQRVVE KELKRAENS

IL-8 is a member of the CXC chemokine family. This family of small basic heparan-binding proteins is proinflammatory and primarily mediates the activation and migration of neutrophils from peripheral blood into tissue. This chemokine is one of the major mediators of the inflammatory response and is secreted by several cell types in response to an inflammatory stimulus. It functions as a chemoattractant, and is also a potent angiogenic factor. IL-8 attracts neutrophils, basophils, and T-cells, but not monocytes. Cystic fibrosis (CF) is characterized by severe lung inflammation. The inflammatory process is believed to be caused by massive overproduction of the proinflammatory protein IL-8, and the high levels of IL8 in the CF lung are therefore believed to be the central mechanism behind CF lung pathophysiology. Human IL-8 Antibody (4H8F8), mAb, Mouse was raised by a genetic immunization technique. Genetic immunization can be used to generate antibodies by directly delivering antigen-coding DNA into the animal, rather than injecting a protein or peptide. The animals cells produce the protein, which stimulates the animals immune system to produce antibodies against that particular protein. A vector coding for a partial fusion protein was used for genetic immunisation of a mouse and the resulting serum was tested in Western blot against an E.coli lysate containing that partial fusion protein. Genetic immunization offers enormous advantages over the traditional protein-based immunization method. DNA is faster, cheaper, and easier to produce and can be produced by standard techniques readily amenable to automation. Furthermore, the antibodies generated by genetic immunization are usually of superior quality with regard to specificity, affinity, and native protein recognization.


ELISA Capture: 0.5-1 µg/ml
ELISA Detection: 0.05-0.2 µg/ml
Western blot: 1-2 µg/ml

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Secreted
Post transnational modification: Citrullination at Arg-27 prevents proteolysis, and dampens tissue inflammation, it also enhances leukocytosis, possibly through impaired chemokine clearance from the blood circulation.
BioGrid: 109790. 12 interactions.
There are currently no product reviews
Write a review on this product!

Customers who purchased this product also purchased

Monoclonal Antibody to Mouse PD-L1 (Clone: 10F.9G2)

Monoclonal Antibody to Mouse P...

details-Monoclonal Antibody to Mouse PD-L1 (Clone: 10F.9G2)
Recombinant human CD96 protein with C-terminal mouse Fc and 6×His tag

Recombinant human CD96 protein...

details-Recombinant human CD96 protein with C-terminal mouse Fc and 6×His tag
Anti-SARS-CoV-2 Nucleocapsid antibody(DM22), Rabbit mAb

Anti-SARS-CoV-2 Nucleocapsid a...

details-Anti-SARS-CoV-2 Nucleocapsid antibody(DM22), Rabbit mAb
Monoclonal Antibody to SARS-CoV-2 Nucleocapsid  (Clone: ABM3F2.1C1)

Monoclonal Antibody to SARS-Co...

details-Monoclonal Antibody to SARS-CoV-2 Nucleocapsid  (Clone: ABM3F2.1C1)
Foxp3/Transcription Factor Staining Kit

Foxp3/Transcription Factor Sta...

details-Foxp3/Transcription Factor Staining Kit
Recombinant human EPHA3 protein with C-terminal mouse Fc and 6×His tag

Recombinant human EPHA3 protei...

details-Recombinant human EPHA3 protein with C-terminal mouse Fc and 6×His tag
Polyclonal Antibody to Gab1 (Phospho-Tyr627)

Polyclonal Antibody to Gab1 (P...

details-Polyclonal Antibody to Gab1 (Phospho-Tyr627)
Anti-Biotin Mab(1D4-C5)

Anti-Biotin Mab(1D4-C5)

details-Anti-Biotin Mab(1D4-C5)
Rabbit Polyclonal Antibody to ERK2(Discontinued)

Rabbit Polyclonal Antibody to ...

details-Rabbit Polyclonal Antibody to ERK2(Discontinued)
Anti-Human CD230 / Prion Antibody (Clone : EM-21)

Anti-Human CD230 / Prion Antib...

details-Anti-Human CD230 / Prion Antibody (Clone : EM-21)
Recombinant Human NGAL/Lipocalin-2/LCN2 (C-6His, E. coli)

Recombinant Human NGAL/Lipocal...

details-Recombinant Human NGAL/Lipocalin-2/LCN2 (C-6His, E. coli)
Recombinant Human Small Proline-Rich Protein 1B

Recombinant Human Small Prolin...

details-Recombinant Human Small Proline-Rich Protein 1B
Anti-CD3 epsilon (activation epitope) APC (Clone : APA1/1)

Anti-CD3 epsilon (activation e...

details-Anti-CD3 epsilon (activation epitope) APC (Clone : APA1/1)
Anti-Human CD172ab Antibody (Clone : SE5A5)

Anti-Human CD172ab Antibody (C...

details-Anti-Human CD172ab Antibody (Clone : SE5A5)

Most viewed Products

Recombinant Human Thioredoxin-Like 4A

Recombinant Human Thioredoxin-Like ...

details-Recombinant Human Thioredoxin-Like 4A
NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line

NF-kB Leeporter™ Luciferase Repor...

details-NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line
Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)

Monoclonal Antibody to Caspase-3 (P...

details-Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)
Polyclonal Antibody to Beta actin

Polyclonal Antibody to Beta actin

details-Polyclonal Antibody to Beta actin
Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)

Monoclonal Antibody to Human IL-1be...

details-Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)
Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)

Monoclonal antibody to Human PD-L1 ...

details-Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)
Monoclonal Antibody to GAPDH (Clone: ABM22C5)

Monoclonal Antibody to GAPDH (Clone...

details-Monoclonal Antibody to GAPDH (Clone: ABM22C5)
ACE2/HEK293 Stable Cell Line

ACE2/HEK293 Stable Cell Line

details-ACE2/HEK293 Stable Cell Line
TLR4/IL-8 Leeporter™ Luciferase Reporter-HeLa Cell Line

TLR4/IL-8 Leeporter™ Luciferase R...

details-TLR4/IL-8 Leeporter™ Luciferase Reporter-HeLa Cell Line
Monoclonal antibody to B7-H4 (Clone: ABM53A6)

Monoclonal antibody to B7-H4 (Clone...

details-Monoclonal antibody to B7-H4 (Clone: ABM53A6)

Related Products

Hamster Anti-Mouse CD3e-BIMA(Discontinued)

Hamster Anti-Mouse CD3e-BIMA(Discontinued)

Anti-CD1a Monoclonal Antibody (Clone:HI149)-APC Conjugated

Anti-CD1a Monoclonal Antibody (Clone:HI149)-APC Conjugated

Anti-CD3 Monoclonal Antibody (Clone:MEM-57)-PE/DyLight Conjugated

Anti-CD3 Monoclonal Antibody (Clone:MEM-57)-PE/DyLight Conjugated

New Products

Recombinant Human IL-28B Protein

Recombinant Human IL-28B Protein

Anti-HLA-E APC Mab (3D12)

Anti-HLA-E APC Mab (3D12)

Recombinant Cynomolgus MDK Protein, hFc Tag

Recombinant Cynomolgus MDK Protein, hFc Tag

close

Please Login to write a Review !!


close

Mouse Monoclonal Antibody to IL-8 (Clone : 4H8F8)(Discontinued)

Product code: 45-1054
*specify in mg or ml

Abeomics Logo

Antibodies & Engineered Cell Lines™

Tel : 858-263-4982

Fax : 858-247-7052

Email : support@abeomics.com

Connect with Us

  • Facebook
  • Twitter
  • Linkedin
  • YouTube

Products

  • Antibodies
  • Cell Lines
  • Ligands and Inhibitors
  • Recombinant Proteins
  • Immune-Check Point
  • Kits and Reagents
  • Tissue Microarray
  • recmAb™
  • sdMAB ™

Services

  • Drug Discovery Screening Services
  • Stable Cell Line Development
  • Protein Production
  • Custom Antibody Development
  • Custom Recombinant Antibody Development

Quick order

+ Add More..

Newsletter

Posters and Flyers

© 2023 Abeomics. All rights reserved.
  • Blog
  • Sitemap
  • Terms
  • Privacy Policy
  • Legal
  • Email unsubscribe

Item added to cart successfully

No cart item available
Continue shopping View Cart