PE-conjugated Anti-ACVR2A antibody(15D6), IgG1 Chimeric mAb
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| Amount : | 100 test |
| Isotype : | Rabbit/Human Fc chimeric IgG1 |
| Purification : | Purified from cell culture supernatant by affinity chromatography |
| Content : | Liquid?PBS?with?0.05%?Proclin300,?1%?BSA |
| Storage condition : | Store?at?2?C-8?C?for?6?months |
| Gene : | ACVR2A |
| Uniprot ID : | P27037 |
| Alternative Name : | ACVR2; ACTRII |
This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jun 2013]
FACS 1/100
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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