PE-conjugated Anti-IL15RA antibody(DM206); Rabbit mAb
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| Amount : | 100 Test |
| Isotype : | Rabbit IgG |
| Purification : | Purified from cell culture supernatant by affinity chromatography |
| Content : | Liquid PBS�with�0.05%�Proclin300,�1%�BSA |
| Storage condition : | Store�at�2�C-8�C�for�6�months |
| Gene : | IL15RA |
| Uniprot ID : | Q13261 |
| Alternative Name : | CD215 |
This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits; IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha; an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA; IL15RA is capable of binding IL15 with high affinity independent of other subunits; which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1:BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.
Flow Cyt 1:100
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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