PE-conjugated Anti-JAM-A antibody(DMC278); IgG1 Chimeric mAb
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| Amount : | 100 Test |
| Isotype : | Rabbit/Human Fc chimeric IgG1 |
| Purification : | Purified from cell culture supernatant by affinity chromatography |
| Content : | Liquid PBS�with�0.05%�Proclin300,�1%�BSA |
| Storage condition : | Store�at�2�C-8�C�for�6�months |
| Gene : | JAM-A |
| Uniprot ID : | Q9Y624 |
| Alternative Name : | CD321; JAM;JAM1; JAMA; JCAM; KAT; PAM-1 |
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets; forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition; the encoded protein can act as (1) a receptor for reovirus; (2) a ligand for the integrin LFA1; involved in leukocyte transmigration; and (3) a platelet receptor. Multiple 5' alternatively spliced variants; encoding the same protein; have been identified but their biological validity has not been established.
Flow Cyt 1:100
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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