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  7. Phospho-PLCg1 (Tyr783) (Clone: C4) rabbit mAb PE conjugate

Phospho-PLCg1 (Tyr783) (Clone: C4) rabbit mAb PE conjugate

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Fig-1: Flow cytometric analysis of Hela cells unstained imatinib treated (blue) or stained treated with imatinib (red) or with pervanadate (green) using phospho-PLCg1 (Tyr783) antibody PLCg1Y783-C4 PE conjugate.

Phospho-PLCg1 (Tyr783) (Clone: C4) rabbit mAb PE conjugate

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Product code: 12-4097

Clone name : PLCG1Y783-C4
Clonality : Monoclonal
Application : FACS
Reactivity : Human
Conjugate : PE

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  •   10 Tests

  •  100 Tests

  • $361.00 

  • $536.00 

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Download TDS MSDS

  • Product Info
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Amount : 100 Tests
Isotype : Rabbit IgG1k
Content : 1X PBS, 0.09% NaN3, 0.2% BSA
Storage condition : Store at 2-8°C. Avoid repeated freeze and thaw cycles.
Alternative Name : 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, PLC-148, Phosphoinositide phospholipase C-gamma-1, Phospholipase C-II, Phospholipase C-gamma-1, PLC-gamma-1, PLC1
Immunogen Information : A synthetic phospho-peptide corresponding to residues surrounding Tyr783 of human phospho PLCg1.

The Phospholipase C (PLC) isozymes hydrolyze phosphatidyl inositolphosphate to inositol triphosphate and diacylglycerol. In response to extracellular stimuli such as hormones, growth factors and neurotransmitters, PLC hydrolyzes phosphatidylinositol 4,5-bisphosphate (PIP2) to generate diacylglycerols (DAGs) and water-soluble phosphorylated derivatives, such as inositol 1,4,5-triphosphate (IP3). Within the PLC family, PLCg is the only member that contains SH2 and SH3 domains, necessary for phospho PLCg activation. Phospho PLCg, upon activation, can interact with receptor tyrosine kinases.

For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells or 5 µL per 100 µL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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Phospho-PLCg1 (Tyr783) (Clone: C4) rabbit mAb PE conjugate

Product code: 12-4097
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