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  7. Polyclonal Antibody to eIF2beta (phospho-Ser2)

Polyclonal Antibody to eIF2beta (phospho-Ser2)

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Figure 1: Western blot analysis of extracts from C2C12 cells untreated or treated with PMA using eIF2b(phospho-Ser2) Antibody 35-1309 .

Polyclonal Antibody to eIF2beta (phospho-Ser2)

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Product code: 35-1309

Clonality : Polyclonal
Application : WB
Reactivity : Rat, Mouse, Human

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  •   50 µl

  •  100 µl

  • $349.00 

  • $412.00 

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Format : Purified
Amount : 100 µl
Isotype : Rabbit IgG
Content : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : EIF2S2
Gene ID : 8894
Uniprot ID : P20042
Alternative Name : EIF2S2, EIF2, EIF2B
Immunogen Information : Peptide sequence around phosphorylation site of serine 2 (M-S(p)-G-D-E) derived from Human eIF2 beta.

eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B. Structure of the beta subunit of translational initiation factor eIF-2. The DNA sequence and comparative analysis of human chromosome 20. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

Predicted MW: 38kd, Western blotting: 1:500~1:1000

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

BioGrid: 114411. 81 interactions.
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Polyclonal Antibody to eIF2beta (phospho-Ser2)

Product code: 35-1309
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