Abeomics Logo
  • (0) Items
    • Items | total: $0.00 (0)
    • Your shopping cart is empty!

Abeomics Logo

Antibodies & Engineered Cell Lines™

  • Account
    • Login
    • Address Book
    • My Order
    • My Wish List
    • Open a New Ticket
  • (0) Items
    • Your shopping cart is empty!

  • About us
  • Products
      • Antibodies
        • Biosimilars
        • TLR and Innate Immunity
        • Apoptosis
        • Immunology
        • DNA methylation and Repair
        • Cell Signalling
        • Infectious Diseases
        • NF-kB Pathway
        • Cancer Marker
        • Loading Controls
        • Stem Cells
        • Development and Differentiation
        • Isotype Controls
        • Secondary Antibodies
        • Tag Antibodies
        • Miscellaneous
      • Cell Lines
        • Reporter Cell Lines
        • Stable Cell Lines
      • Ligands and Inhibitors
        • Peptide Inhibitors
        • Proteases inhibitors
        • TLR Ligands
        • Caspase Inhibitors
      • Recombinant Proteins
        • Recombinant Proteins
      • Immune-Check Point
      • Kits and Reagents
        • Other Kits
        • Luciferase reporter assay kits
        • Inhibitor Screening Kit
        • ELISA Kits
        • Molecular Biology Kits
        • Apoptosis Detection kits
        • Flowcytometry staining kits
        • Cell dissociation solutions
        • Western Blot membranes (Quick blots/ Q Blots)
      • Tissue Microarray
      • recmAb™
        • Recombinant Biosimilar Antibodies
        • Recombinant Rabbit Antibodies
        • Recombinant Mouse Antibodies
      • sdMAB ™
        • Shark sdMAB ™
        • Alpaca sdMAB ™
  • Pathways
      • All-Pathways

        View all pathways

      • interactive-pathways

        View all interactive pathways

  • Custom Service
    • Drug Discovery Screening Services
    • Stable Cell Line Development
    • Protein Production
    • Custom Antibody Development
    • Custom Recombinant Antibody Development
  • Quick order
    • + Add More..

  • Support
  • Contact us
  • Distributors
  1. Catalog
  2. /
  3. Antibodies
  4. /
  5. Cell Signalling
  6. /
  7. Polyclonal Antibody to PKC Zeta(Phospho-Thr410)

Polyclonal Antibody to PKC Zeta(Phospho-Thr410)

Share:

Figure 1: Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using PKC? (Phospho-Thr410) antibody (35-1283 ).

Polyclonal Antibody to PKC Zeta(Phospho-Thr410)

Roll over image to zoom in

   

Product code: 35-1283

Clonality : Polyclonal
Application : IHC
Reactivity : Rat, Mouse, Human

Shipping Info:

For estimated delivery dates, please contact us at support@abeomics.com

Download TDS MSDS
Write a review for this product on BioCompare
Get $20 gift card from Amazon
Size
Price

Available Pack Size(s)

  •   50 µl

  •  100 µl

  • $349.00 

  • $412.00 

Bulk Order

Add to Wish List

Shipping Info:

For estimated delivery dates, please contact us at support@abeomics.com

Download TDS MSDS

  • Product Info
  • Antigen Details
  • Description
  • Application Note
  • More
  • Review   (0)
Format : Purified
Amount : 100 µl
Isotype : Rabbit IgG
Content : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : PRKCZ
Gene ID : 5590
Uniprot ID : Q05513
Alternative Name : PKC2, PKC-ZETA
Immunogen Information : Peptide sequence around phosphorylation site of tyrosine 279/216 (V-S-Y(p)-I-C) derived from Human GSK3 alpha/beta.

Calcium- and diacylglycerol-independent serine/threonine-protein kinase that functions in phosphatidylinositol 3-kinase (PI3K) pathway and mitogen-activated protein (MAP) kinase cascade, and is involved in NF-kappa-B activation, mitogenic signaling, cell proliferation, cell polarity, inflammatory response and maintenance of long-term potentiation (LTP). Upon lipopolysaccharide (LPS) treatment in macrophages, or following mitogenic stimuli, functions downstream of PI3K to activate MAP2K1/MEK1-MAPK1/ERK2 signaling cascade independently of RAF1 activation. Required for insulin-dependent activation of AKT3, but may function as an adapter rather than a direct activator. Upon insulin treatment may act as a downstream effector of PI3K and contribute to the activation of translocation of the glucose transporter SLC2A4/GLUT4 and subsequent glucose transport in adipocytes. In EGF-induced cells, binds and activates MAP2K5/MEK5-MAPK7/ERK5 independently of its kinase activity and can activate JUN promoter through MEF2C. Through binding with SQSTM1/p62, functions in interleukin-1 signaling and activation of NF-kappa-B with the specific adapters RIPK1 and TRAF6. Participates in TNF-dependent transactivation of NF-kappa-B by phosphorylating and activating IKBKB kinase, which in turn leads to the degradation of NF-kappa-B inhibitors. In migrating astrocytes, forms a cytoplasmic complex with PARD6A and is recruited by CDC42 to function in the establishment of cell polarity along with the microtubule motor and dynein. In association with FEZ1, stimulates neuronal differentiation in PC12 cells. In inflammatory response, is required for the T-helper 2 (Th2) differentiation process, including interleukins production, efficient activation of JAK1 and the subsequent phosphorylation and nuclear translocation of STAT6. May be involved in development of allergic airway inflammation (asthma), a process dependent on Th2 immune response. In NF-kappa-B-mediated inflammatory response, can relieve the SETD6-dependent repression of NF-kappa-B target genes by phosphorylating the RELA subunit at 'Ser-311'. Is necessary and sufficient for LTP maintenance in hippocampal CA1 pyramidal cells.

Predicted MW: 78kd, Immunohistochemistry: 1:50~1:100

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cytoplasm
Post transnational modification: CDH5 is required for its phosphorylation at Thr-410. Phosphorylated by protein kinase PDPK1; phosphorylation is inhibited by the apoptotic C-terminal cleavage product of PKN2. Phosphorylation at Thr-410 by PI3K activates the kinase.
Tissue Specificity: Expressed in brain, and to a lesser extent in lung, kidney and testis.
BioGrid: 111576. 90 interactions.
There are currently no product reviews
Write a review on this product!

Customers who purchased this product also purchased

Recombinant Human MICA Protein with C-terminal 6×His tag

Recombinant Human MICA Protein...

details-Recombinant Human MICA Protein with C-terminal 6×His tag
BCL10 Recombinant Protein

BCL10 Recombinant Protein

details-BCL10 Recombinant Protein
Recombinant Protein G His Tag

Recombinant Protein G His Tag

details-Recombinant Protein G His Tag
Recombinant human CD40 protein with C-terminal mouse Fc and 6×His tag

Recombinant human CD40 protein...

details-Recombinant human CD40 protein with C-terminal mouse Fc and 6×His tag
Recombinant 2019-nCoV S Protein RBD (K417N, E484K, N501Y, Mammalian, C-His)

Recombinant 2019-nCoV S Protei...

details-Recombinant 2019-nCoV S Protein RBD (K417N, E484K, N501Y, Mammalian, C-His)
Anti-CD28 antibody(DM63), Rabbit mAb

Anti-CD28 antibody(DM63), Rabb...

details-Anti-CD28 antibody(DM63), Rabbit mAb
Anti-Human CD194 (CCR4) (Mogamulizumab) – Fc Muted™ Biotin

Anti-Human CD194 (CCR4) (Mogam...

details-Anti-Human CD194 (CCR4) (Mogamulizumab) – Fc Muted™ Biotin
Recombinant human GITR Ligand protein with N-terminal mouse Fc and C-6×His tag

Recombinant human GITR Ligand ...

details-Recombinant human GITR Ligand protein with N-terminal mouse Fc and C-6×His tag
Anti-PD-L1 VHH antibody

Anti-PD-L1 VHH antibody

details-Anti-PD-L1 VHH antibody

Most viewed Products

Recombinant Human Thioredoxin-Like 4A

Recombinant Human Thioredoxin-Like ...

details-Recombinant Human Thioredoxin-Like 4A
NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line

NF-kB Leeporter™ Luciferase Repor...

details-NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line
Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)

Monoclonal Antibody to Caspase-3 (P...

details-Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)
Polyclonal Antibody to Beta actin

Polyclonal Antibody to Beta actin

details-Polyclonal Antibody to Beta actin
Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)

Monoclonal Antibody to Human IL-1be...

details-Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)
Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)

Monoclonal antibody to Human PD-L1 ...

details-Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)
Monoclonal Antibody to GAPDH (Clone: ABM22C5)

Monoclonal Antibody to GAPDH (Clone...

details-Monoclonal Antibody to GAPDH (Clone: ABM22C5)
ACE2/HEK293 Stable Cell Line

ACE2/HEK293 Stable Cell Line

details-ACE2/HEK293 Stable Cell Line
TLR4/IL-8 Leeporter™ Luciferase Reporter-HeLa Cell Line

TLR4/IL-8 Leeporter™ Luciferase R...

details-TLR4/IL-8 Leeporter™ Luciferase Reporter-HeLa Cell Line
Monoclonal antibody to B7-H4 (Clone: ABM53A6)

Monoclonal antibody to B7-H4 (Clone...

details-Monoclonal antibody to B7-H4 (Clone: ABM53A6)

Related Products

Anti-HSP60 Monoclonal Antibody (Clone : LK1) Alkaline Phosphatase

Anti-HSP60 Monoclonal Antibody (Clone : LK1) Alkaline Phosphatase

Anti-HSP22 Monoclonal Antibody (Clone : 3C12-H11) - APC

Anti-HSP22 Monoclonal Antibody (Clone : 3C12-H11) - APC

Polyclonal Antibody to SMO

Polyclonal Antibody to SMO

New Products

Recombinant Human LYPD3(31-325) Protein, His Tag

Recombinant Human LYPD3(31-325) Protein, His Tag

Recombinant Human TPSAB1 Protein, His Tag

Recombinant Human TPSAB1 Protein, His Tag

Recombinant Human TEM1 Protein, His Tag

Recombinant Human TEM1 Protein, His Tag

close

Please Login to write a Review !!


close

Polyclonal Antibody to PKC Zeta(Phospho-Thr410)

Product code: 35-1283
*specify in mg or ml

Abeomics Logo

Antibodies & Engineered Cell Lines™

Tel : 858-263-4982

Fax : 858-247-7052

Email : support@abeomics.com

Connect with Us

  • Facebook
  • Twitter
  • Linkedin
  • YouTube

Products

  • Antibodies
  • Cell Lines
  • Ligands and Inhibitors
  • Recombinant Proteins
  • Immune-Check Point
  • Kits and Reagents
  • Tissue Microarray
  • recmAb™
  • sdMAB ™

Services

  • Drug Discovery Screening Services
  • Stable Cell Line Development
  • Protein Production
  • Custom Antibody Development
  • Custom Recombinant Antibody Development

Quick order

+ Add More..

Newsletter

Posters and Flyers

© 2023 Abeomics. All rights reserved.
  • Blog
  • Sitemap
  • Terms
  • Privacy Policy
  • Legal
  • Email unsubscribe

Item added to cart successfully

No cart item available
Continue shopping View Cart