Recombinant Human ADAMTS1 Protein, His Tag
|Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.
|Storage condition :
|Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
|Uniprot ID :
|Alternative Name :
|ADAM-TS 1, ADAM-TS1, ADAMTS-1, METH-1
Molecular weight: The protein has a predicted molecular mass of 101.1 kDa after removal of the signal peptide. The apparent molecular mass of ADAMTS1-His is approximately 100-130 kDa due to glycosylation.
Description: Recombinant human ADAMTS1 Protein with C-terminal 6×His tag
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function.