Recombinant Human BAFF protein with N-terminal human Fc
|Amount :||50 µg|
|Purification :||The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.|
|Content :||Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.|
|Storage condition :||Store at -80°C for 12 months (Avoid repeated freezing and thawing)|
|AA sequence :||hFc（Glu99-Ala330）+BAFF（Ala134-Leu285）|
|Uniprot ID :||Q9Y275|
|Alternative Name :||TNFSF13B,BAFF,BLYS,CD257,DTL,TALL1,THANK,TNFSF20,ZTNF4,TALL-1|
Expression Host : HEK293
The protein has a predicted molecular mass of 43.2 kDa after removal of the signal peptide.The apparent molecular mass of BAFF-hFc is approximately 50-55 kDa due to glycosylation.
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified.