Recombinant Human X-Ray Repair Cross Complementing Protein 2
|Amount :||20 µg|
|Purification :||Greater than 80% as determined by SDS-PAGE.|
|Content :||The XRCC2 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.|
|Storage condition :||Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.|
|AA sequence :||MGSSHHHHHH SSGLVPRGSH MGSMCSAFHR AESGTELLAR LEGRSSLKEI EPNLFADEDS PVHGDILEFH GPEGTGKTEM LYHLTARCIL PKSEGGLEVE VLFIDTDYHF DMLRLVTILE HRLSQSSEEI IKYCLGRFFL VYCSSSTHLL LTLYSLESMF CSHPSLCLLI LDSLSAFYWI DRVNGGESVN LQESTLRKCS QCLEKLVNDY RLVLFATTQT IMQKASSSSE EPSHASRRLC DVDIDYRPYL CKAWQQLVKH RMFFSKQDDS QSSNQFSLVS RCLKSNSLKK HFFIIGESGV EFC|
|Alternative Name :||X-Ray Repair Complementing Defective Repair In Chinese Hamster Cells 2, X-Ray Repair Cross-Complementing Protein 2, RAD51-like, DNA Repair Protein XRCC2.|
Source : Escherichia Coli. XRCC2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 303 amino acids (1-280) and having a molecular mass of 34.3 kDa. XRCC2 is fused to a 23 amino acid His-tag at N-terminus. XRCC2 belongs to the RecA/Rad51-related protein family which takes part in homologous recombination to repair DNA damage and preserve chromosome stability. XRCC2 gene participates in the mending of DNA double-strand disruptions by homologous recombination. Additionally, XRCC2 functionally complements Chinese hamster irs1, a repair-deficient mutant which displays hypersensitivity to diverse DNA-damaging agents.