SARS-CoV-2 (2019-nCoV) Spike S1 South African Mutant (K417N / E484K / N501Y) His Tag Protein
Figure-1: Recombinant SARS-CoV-2 Spike S1 (K417N / E484K / N501Y) mutant protein was run on a 4-20% SDS-PAGE gel followed by Coomassie blue staining.
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| Amount : | 100 μg |
| Purification : | >95% by SDS-PAGE. |
| Content : | PBS and 10% Glycerol. |
| Storage condition : | SARS-CoV-2 Spike S1 South African Mutant His Protein is shipped on ice packs. Upon arrival, Store at -20°C. Do not freeze-thaw multiple times. |
| AA sequence : | The target protein is expressed with sequence (AA 14-683) of SARS-CoV-2/COVID-19 Spike S1 sequence with mutation at 614aa fused with a 6×His tag in C-Terminal. |
Source: SARS-CoV-2 (2019-nCoV) Spike S1 K417N / E484K / N501Y (South African variant) protein was expressed in CHO-K1. The spike S1 protein of coronavirus (CoV2) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
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