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  5. SARS-CoV-2 (2019-nCoV) Spike S1 South African Mutant (K417N / E484K / N501Y) His Tag Protein

SARS-CoV-2 (2019-nCoV) Spike S1 South African Mutant (K417N / E484K / N501Y) His Tag Protein

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Figure-1: Recombinant SARS-CoV-2 Spike S1 (K417N / E484K / N501Y) mutant protein was run on a 4-20% SDS-PAGE gel followed by Coomassie blue staining.

SARS-CoV-2 (2019-nCoV) Spike S1 South African Mutant (K417N / E484K / N501Y) His Tag Protein
SARS-CoV-2 (2019-nCoV) Spike S1 South African Mutant (K417N / E484K / N501Y) His Tag Protein
SARS-CoV-2 (2019-nCoV) Spike S1 South African Mutant (K417N / E484K / N501Y) His Tag Protein

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Figure-1: Recombinant SARS-CoV-2 Spike S1 (K417N / E484K / N501Y) mutant protein was run on a 4-20% SDS-PAGE gel followed by Coomassie blue staining.
Figure-2: Western blot analysis of SARS-CoV-2 Spike S1 (K417N / E484K / N501Y) mutant protein. Anti-Spike S1 antibody was used in western Blot analysis.
Figure-3:Comparative binding of Spike S1 variants to sACE2: Wells of a 96-well microtiter plate were coated with 100 ng in duplicates each of S1-WT (Cat# 21-1008), S1-N439K (Cat# 21-1012), S1-D614G (Cat# 21-1009), S1-South Africa (Cat# 21-1017), and S1-Southern California (Cat# 21-1018). Binding to sACE2 was determined by adding different concentrations of biotinylated-sACE2 (Cat# 21-1006).

Product code: 21-1017

Application : ELISA, WB

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Order now and get it on Tuesday January 31, 2023

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Same-day delivery in San Diego available for the following zip codes:

92121, 92122, 92037, 92117, 92109, 92110, 92101, 92010, 92011, 92009, 92008
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  •   50 µg

  •  100 μg

  • $285.00 

  • $405.00 

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Order now and get it on Tuesday January 31, 2023

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Amount : 100 μg
Purification : >95% by SDS-PAGE.
Content : PBS and 10% Glycerol.
Storage condition : SARS-CoV-2 Spike S1 South African Mutant His Protein is shipped on ice packs. Upon arrival, Store at -20°C. Do not freeze-thaw multiple times.
AA sequence : The target protein is expressed with sequence (AA 14-683) of SARS-CoV-2/COVID-19 Spike S1 sequence with mutation at 614aa fused with a 10×His tag in C-Terminal.

Source: SARS-CoV-2 (2019-nCoV) Spike S1 K417N / E484K / N501Y (South African variant) protein was expressed in CHO-K1. The spike S1 protein of coronavirus (CoV2) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

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SARS-CoV-2 (2019-nCoV) Spike S1 South African Mutant (K417N / E484K / N501Y) His Tag Protein

Product code: 21-1017
*specify in mg or ml

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