VAMP2 (1-94) Human
|Amount :||5 µg|
|Purification :||Greater than 95.0% as dtermined by SDS-PAGE.|
|Content :||VAMP2 protein solution (0.5mg/ml) containing Phosphate buffered saline (pH 7.4) and 10% Glycerol 0.1mM PMSF.|
|Storage condition :||Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.|
|AA sequence :||MGSSHHHHHH SSGLVPRGSH MGSHMSATAA TAPPAAPAGE GGPPAPPPNL TSNRRLQQTQ AQVDEVVDIM RVNVDKVLER DQKLSELDDR ADALQAGASQ FETSAAKLKR KYWWKNLK.|
|Alternative Name :||Vesicle Associated Membrane Protein 2, Synaptobrevin 2, VAMP-2, SYB2, Vesicle-Associated Membrane Protein 2, Synaptobrevin-2, Vesicle-associated membrane protein 2.|
Sterile Filtered colorless solution.
Synaptobrevin 2 which is an 18 kDa integral membrane protein localized to the cytoplasmic surface of synaptic vesicle, consists of a proline-rich N-terminal region, a highly conserved hydrophilic domain, followed by a transmembrane anchor and a C-terminal. Synaptobrevin 2 is predominantly expressed in Langerhans islets and glomerular cells. The N-terminal domain of the protein (residues 1-89) forms a specific SNARE complex with the target membrane-associated t- or Q-SNAREs syntaxin 1 and SNAP-25.
VAMP2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 118 amino acids (1-94 a.a) and having a molecular mass of 12.8kDa.VAMP2 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.