Abeomics Logo
  • (0) Items
    • Items | total: $0.00 (0)
    • Your shopping cart is empty!

Abeomics Logo

Antibodies & Engineered Cell Lines™

  • Account
    • Login
    • Address Book
    • My Order
    • My Wish List
    • Open a New Ticket
  • (0) Items
    • Your shopping cart is empty!

  • About us
  • Products
      • Antibodies
        • Biosimilars
        • TLR and Innate Immunity
        • Apoptosis
        • Immunology
        • DNA methylation and Repair
        • Cell Signalling
        • Infectious Diseases
        • NF-kB Pathway
        • Cancer Marker
        • Loading Controls
        • Stem Cells
        • Development and Differentiation
        • Isotype Controls
        • Secondary Antibodies
        • Tag Antibodies
        • Miscellaneous
      • Cell Lines
        • Reporter Cell Lines
        • Stable Cell Lines
      • Ligands and Inhibitors
        • Peptide Inhibitors
        • Proteases inhibitors
        • TLR Ligands
        • Caspase Inhibitors
      • Recombinant Proteins
        • Recombinant Proteins
      • Immune-Check Point
      • Kits and Reagents
        • Luciferase reporter assay kits
        • Inhibitor Screening Kit
        • ELISA Kits
        • Molecular Biology Kits
        • Apoptosis Detection kits
        • Flowcytometry staining kits
        • Cell dissociation solutions
        • Western Blot membranes (Quick blots/ Q Blots)
      • Tissue Microarray
      • recmAb™
        • Recombinant Biosimilar Antibodies
        • Recombinant Rabbit Antibodies
        • Recombinant Mouse Antibodies
  • Pathways
      • All-Pathways

        View all pathways

      • interactive-pathways

        View all interactive pathways

  • Custom Service
    • Drug Discovery Screening Services
    • Stable Cell Line Development
    • Protein Production
    • Custom Antibody Development
  • Quick order
    • + Add More..

  • Support
  • Contact us
  • Distributors
  1. Catalog
  2. /
  3. Kits and Reagents
  4. /
  5. ELISA Kits
  6. /
  7. ACE2 (human) ELISA Kit

ACE2 (human) ELISA Kit

Share:

Figure 1: Human ACE2 Standard Curve.

ACE2 (human) ELISA Kit

Roll over image to zoom in

   

Product code: 90-7008

Reactivity : Human

Shipping Info:

For estimated delivery dates, please contact us at support@abeomics.com

Download TDS / Manual MSDS
Write a review for this product on BioCompare
Get $20 gift card from Amazon
Size
Price
1 x 96 Tests
$525.00 

Add to Wish List

Bulk Order

Shipping Info:

For estimated delivery dates, please contact us at support@abeomics.com

Download TDS / Manual MSDS

  • Product Info
  • Description
  • Review   (0)
Amount : 1 x 96 Tests
Storage condition : 12 months after the day of manufacturing. See expiry date on ELISA Kit box.
Alternative Name : SARS-CoV-2 Receptor; Angiotensin-converting Enzyme 2; Angiotensin-converting Enzyme Homolog; Angiotensin-converting Enzyme-related Carboxypeptidase; Metalloprotease MPROT15

Detects human ACE2 in serum, plasma, urine and cell culture supernatant.Human ACE2 gene, localized in X chromosome, encodes for a 805 amino acid protein with an N-terminal signal sequence, a metalloprotease zinc binding site (HEMGH) and a hydrophobic region near the C-terminus acting as a membrane anchor (transmembrane domain). Angiotensin-converting enzyme 2 (ACE2) is a type I transmembrane metallocarboxypeptidase within the renin-angiotensin system (RAS), which plays a key role in blood pressure regulation, fluid and electrolyte balance, thirst, cardiac/renal function and growth. ACE2 is expressed on the cell surface of type 2 alveolar epithelial cells in the lungs as well as on cells in many other tissues. ACE2 shares approximately 60% homology with ACE, the other key enzyme of the RAS system. ACE2 converts angiotensin II (Ang II) into Ang (1-7), which acts on the Mas receptor and plays a role in cardiovascular disease to lower blood pressure through vasodilation and by promoting kidney sodium and water excretion, but also to lower inflammation. The effects of ACE2 directly oppose those induced by ACE-Ang II signaling, whereby ACE converts Ang I into Ang II, which increases blood pressure by inducing vasoconstriction, increasing kidney reabsorption of sodium and water and promoting inflammation.

ACE2 has been identified as a key receptor on target cells for SARS-CoV infections in 2002. ACE2 functions as the entry receptor of the new SARS-CoV-2 coronavirus that emerged in China in 2019 and is the cause of the new disease COVID-19. Strong binding of the spike protein of SARS-CoV-2 to ACE2, along with proteolytic cleavage of ACE2 by transmembrane serine protease 2 (TMPRSS2), facilitates entry of the virus into cells, viral replication and cell-to-cell transmission.

ACE2 can undergo an ADAM17 (a disintegrin and metalloproteinase 17)-mediated “shedding” from endothelial cells, resulting in the release of the ectodomain into the circulation. This soluble form may act as a competitive interceptor of SARS-CoV-2 and other coronaviruses by preventing binding of the viral particle to the surface-bound, full-length ACE2. Soluble ACE2 might also be used as biomarker of hypertension and cardiovascular diseases.

There are currently no product reviews
Write a review on this product!

Customers who purchased this product also purchased

Monoclonal Antibody to human VCAM-1

Monoclonal Antibody to human V...

details-Monoclonal Antibody to human VCAM-1
Monoclonal Antibody to Galectin 13 (Clone: ABM4E42) No Azide, No BSA

Monoclonal Antibody to Galecti...

details-Monoclonal Antibody to Galectin 13 (Clone: ABM4E42) No Azide, No BSA
Recombinant Hepatitis B Surface Antigen preS2

Recombinant Hepatitis B Surfac...

details-Recombinant Hepatitis B Surface Antigen preS2
Recombinant Human Transmembrane Protein 27

Recombinant Human Transmembran...

details-Recombinant Human Transmembrane Protein 27
Anti-Cytokeratin 7+17 Monoclonal Antibody (Clone:C-46)

Anti-Cytokeratin 7+17 Monoclon...

details-Anti-Cytokeratin 7+17 Monoclonal Antibody (Clone:C-46)
BCOADC-E2 Recombinant Protein

BCOADC-E2 Recombinant Protein

details-BCOADC-E2 Recombinant Protein
Anti-TACSTD2 / TROP2 (Epithelial Marker) Monoclonal Antibody(Clone: TACSTD2/2151)

Anti-TACSTD2 / TROP2 (Epitheli...

details-Anti-TACSTD2 / TROP2 (Epithelial Marker) Monoclonal Antibody(Clone: TACSTD2/2151)
Recombinant MPXV A29L Protein, C-term His (E. Coli)

Recombinant MPXV A29L Protein,...

details-Recombinant MPXV A29L Protein, C-term His (E. Coli)
Anti-SARS-CoV-2 Nucleocapsid antibody(DM38), Rabbit mAb

Anti-SARS-CoV-2 Nucleocapsid a...

details-Anti-SARS-CoV-2 Nucleocapsid antibody(DM38), Rabbit mAb
Coronavirus (COVID-19) Spike Antibody

Coronavirus (COVID-19) Spike A...

details-Coronavirus (COVID-19) Spike Antibody
Anti-Human OX40L (Oxelumab) – APC

Anti-Human OX40L (Oxelumab) –...

details-Anti-Human OX40L (Oxelumab) – APC
rMMP 9 Recombinant Protein

rMMP 9 Recombinant Protein

details-rMMP 9 Recombinant Protein
Recombinant E.Coli Superoxide Dismutase

Recombinant E.Coli Superoxide ...

details-Recombinant E.Coli Superoxide Dismutase
oLeptin tA PEG Recombinant Protein

oLeptin tA PEG Recombinant Pro...

details-oLeptin tA PEG Recombinant Protein

Most viewed Products

Recombinant Human Thioredoxin-Like 4A

Recombinant Human Thioredoxin-Like ...

details-Recombinant Human Thioredoxin-Like 4A
NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line

NF-kB Leeporter™ Luciferase Repor...

details-NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line
Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)

Monoclonal Antibody to Human IL-1be...

details-Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)
Polyclonal Antibody to Beta actin

Polyclonal Antibody to Beta actin

details-Polyclonal Antibody to Beta actin
Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)

Monoclonal Antibody to Caspase-3 (P...

details-Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)
Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)

Monoclonal antibody to Human PD-L1 ...

details-Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)
Monoclonal Antibody to GAPDH (Clone: ABM22C5)

Monoclonal Antibody to GAPDH (Clone...

details-Monoclonal Antibody to GAPDH (Clone: ABM22C5)
Recombinant Human Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His)

Recombinant Human Indoleamine 2,3-D...

details-Recombinant Human Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His)
Monoclonal antibody to B7-H4 (Clone: ABM53A6)

Monoclonal antibody to B7-H4 (Clone...

details-Monoclonal antibody to B7-H4 (Clone: ABM53A6)
Polyclonal Antibody to Beta Tubulin

Polyclonal Antibody to Beta Tubulin

details-Polyclonal Antibody to Beta Tubulin

Related Products

Human IL-5 (Interleukin 5) Pre-Coated ELISA Kit

Human IL-5 (Interleukin 5) Pre-Coated ELISA Kit

Human IL-35 (Interleukin 35) Pre-Coated ELISA Kit

Human IL-35 (Interleukin 35) Pre-Coated ELISA Kit

Human IL-3 (Interleukin 3) Pre-Coated ELISA Kit

Human IL-3 (Interleukin 3) Pre-Coated ELISA Kit

New Products

Recombinant Human Max dimerizer 3/MXD3(C-His)

Recombinant Human Max dimerizer 3/MXD3(C-His)

Anti-CD73 antibody(DM204), Rabbit mAb

Anti-CD73 antibody(DM204), Rabbit mAb

Recombinant Human GCSH Protein

Recombinant Human GCSH Protein

close

Please Login to write a Review !!


close

ACE2 (human) ELISA Kit

Product code: 90-7008
*specify in mg or ml

Abeomics Logo

Antibodies & Engineered Cell Lines™

Tel : 858-263-4982

Fax : 858-247-7052

Email : support@abeomics.com

Connect with Us

  • Facebook
  • Twitter
  • Linkedin
  • YouTube

Products

  • Antibodies
  • Cell Lines
  • Ligands and Inhibitors
  • Recombinant Proteins
  • Immune-Check Point
  • Kits and Reagents
  • Tissue Microarray
  • recmAb™

Services

  • Drug Discovery Screening Services
  • Stable Cell Line Development
  • Protein Production
  • Custom Antibody Development

Quick order

+ Add More..

Newsletter

Posters and Flyers

© 2023 Abeomics. All rights reserved.
  • Blog
  • Sitemap
  • Terms
  • Privacy Policy
  • Legal
  • Email unsubscribe

Item added to cart successfully

No cart item available
Continue shopping View Cart