ADRA1B Stable Cell Line-CHO-K1-Human(Currently Unavailable)
Figure 1: Functional analysis of ADRA1B receptor.
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| Amount : | 2 vials |
| Content : | Each Vial contains cells in 45% culture medium, 45%FBS, and 10%DMSO |
| Storage condition : | Immediately upon receipt, store in liquid nitrogen. |
| Alternative Name : | Human Recombinant ADRA1B Adrenoceptors Stable Cell Line |
The alpha 1-adrenergic receptor (AR) family consists of three closely related gene products ( alpha 1A, alpha 1B, and alpha 1D). They mediate the actions of norepinephrine (NE) and epinephrine in sympathetically innervated tissues and brain. alpha 1-ARs belong to the G protein-coupled receptor family and consist of single polypeptide chains that are predicted to form seven transmembrane spanning domains. With similar pharmacological and signaling properties, alpha 1-AR subtypes act through Gq/11 proteins to activate phospholipase C, increase inositol 1,4,5-trisphosphate production, and increase intracellular Ca2+. ADRA1B functions in diverse settings include vasoconstriction and myocardial contractility, neuronal dopaminergic responses, dendritic cell migration and inflammatory responses, as well as neuroendocrine regulation of fertility.
Application: Screen for antibodies through Flow Cytometry, Immunocytochemistry or Western blotting and analyzing receptors. Culture Medium: Ham's F12, 10% FBS, 400 µg/ml G418
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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